A fatal case of pulmonary cryptococcosis in an apparently immunocompetent patient from Cote D′ Ivoire

Cryptococcosis is an opportunistic mycosis caused by Cryptococcus, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a...

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Bibliographic Details
Main Authors: Ahou Sandrine Konan, Kalou Dibert Zika, Affoué Sandrine Josette Kouakou, Appi Sandrine Kouamé, Malick Senanminfoun Soro, Koffi Daho Adoubryn
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Medical Mycology Case Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S2211753925000107
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Summary:Cryptococcosis is an opportunistic mycosis caused by Cryptococcus, mainly affecting the immunocompromised. We report a case of pulmonary cryptococcosis within a 31-year-old immunocompetent patient admitted for painful chest swelling evolving for 4 months prior to admission. The chest X-Ray showed a rounded pulmonary opacity. The chest ultrasound revealed a pulmonary abscess diffusing under the skin. Direct examination using the Indian ink and the May-Grunwald Giemsa staining revealed encapsulated yeasts in the pus. The Culture of the pus on the Sabouraud medium with chloramphenicol confirmed the presence of Cryptococcus neoformans. Cryptococcal antigen was positive. This case reminds us that cryptococcosis should be considered even without immunosuppression.
ISSN:2211-7539