A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder

Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder is very rare. Definite treatment strategy has not been established and prognosis of the disease is not clear yet. We report a case of primary LCNEC of the urinary bladder here with some review of the literature. The patient was a 84-...

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Main Authors: Shinro Hata, Yoshihisa Tasaki
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2013/804136
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author Shinro Hata
Yoshihisa Tasaki
author_facet Shinro Hata
Yoshihisa Tasaki
author_sort Shinro Hata
collection DOAJ
description Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder is very rare. Definite treatment strategy has not been established and prognosis of the disease is not clear yet. We report a case of primary LCNEC of the urinary bladder here with some review of the literature. The patient was a 84-year-old man. He underwent transurethral resection of bladder tumor (TURBT). Histological examination revealed a rosette arrangement of the tumor cells by HE staining and immunohistochemical study revealed positive CD 56, synaptophysin, and chromogranin A (LCNEC). After TURBT, he has no sign of recurrence for 8 months. We have to strictly observe the progress because LCNEC is very aggressive.
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spelling doaj-art-148396920d23406abc58a7b498736ba02025-02-03T05:57:31ZengWileyCase Reports in Medicine1687-96271687-96352013-01-01201310.1155/2013/804136804136A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary BladderShinro Hata0Yoshihisa Tasaki1Department of Urology, National Hospital Organization Beppu Medical Center, 1473 Uchikamado, Beppu City, Oita 874-0011, JapanDepartment of Urology, National Hospital Organization Beppu Medical Center, 1473 Uchikamado, Beppu City, Oita 874-0011, JapanLarge cell neuroendocrine carcinoma (LCNEC) of the urinary bladder is very rare. Definite treatment strategy has not been established and prognosis of the disease is not clear yet. We report a case of primary LCNEC of the urinary bladder here with some review of the literature. The patient was a 84-year-old man. He underwent transurethral resection of bladder tumor (TURBT). Histological examination revealed a rosette arrangement of the tumor cells by HE staining and immunohistochemical study revealed positive CD 56, synaptophysin, and chromogranin A (LCNEC). After TURBT, he has no sign of recurrence for 8 months. We have to strictly observe the progress because LCNEC is very aggressive.http://dx.doi.org/10.1155/2013/804136
spellingShingle Shinro Hata
Yoshihisa Tasaki
A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
Case Reports in Medicine
title A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
title_full A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
title_fullStr A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
title_full_unstemmed A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
title_short A Case of the Large Cell Neuroendocrine Carcinoma of the Urinary Bladder
title_sort case of the large cell neuroendocrine carcinoma of the urinary bladder
url http://dx.doi.org/10.1155/2013/804136
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AT yoshihisatasaki acaseofthelargecellneuroendocrinecarcinomaoftheurinarybladder
AT shinrohata caseofthelargecellneuroendocrinecarcinomaoftheurinarybladder
AT yoshihisatasaki caseofthelargecellneuroendocrinecarcinomaoftheurinarybladder