Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development.

Chondroitin/dermatan sulfate glycosyltransferase genes are essential for craniofacial development.

Chondroitin/dermatan sulfate (CS/DS) proteoglycans are indispensable for animal development and homeostasis but the large number of enzymes involved in their biosynthesis have made CS/DS function a challenging problem to study genetically. In our study, we generated loss-of-function alleles in zebra...

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Main Authors: Judith Habicher, Gaurav K Varshney, Laura Waldmann, Daniel Snitting, Amin Allalou, Hanqing Zhang, Abdurrahman Ghanem, Caroline Öhman Mägi, Tabea Dierker, Lena Kjellén, Shawn M Burgess, Johan Ledin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-02-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010067&type=printable
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