Combined cerebral oxygen saturation and neuron-specific enolase evaluation for diagnosis and prognosis of sepsis-associated encephalopathy

Combined cerebral oxygen saturation and neuron-specific enolase evaluation for diagnosis and prognosis of sepsis-associated encephalopathy

Abstract Sepsis-associated encephalopathy (SAE) represents a severe neurological complication in sepsis, characterized by high mortality and cognitive impairment. Although clinical significance, SAE lacks effective diagnostic and prognostic tools. This study evaluates the predictive value of neuron-...

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Bibliographic Details
Main Authors: Qian Zhang, Xujie Zhang, Yi Li, Lingwei Zeng, Runyin Zhu, Yan Xin, Lixia Liu, Zhenjie Hu, Yan Huo
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Sepsis-associated encephalopathy(SAE)
Neuron-specific enolase(NSE)
Regional cerebral oxygen saturation(rSO₂)
Egional cerebral oxygen saturation variability (rSO₂%)
Prognosis
Diagnosis
Online Access:https://doi.org/10.1038/s41598-025-00353-3
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