Management of a Parturient with Mast Cell Activation Syndrome: An Anesthesiologist’s Experience

Mast cell activation syndrome (MCAS) is a disorder in which patients experience symptoms and signs attributable to inappropriate mast cell activation and mediator release. Multiorgan involvement in patients can result in significant morbidity and possible mortality. Limited literature exists regardi...

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Bibliographic Details
Main Authors: Sangeeta Kumaraswami, Gabriel Farkas
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Anesthesiology
Online Access:http://dx.doi.org/10.1155/2018/8920921
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Summary:Mast cell activation syndrome (MCAS) is a disorder in which patients experience symptoms and signs attributable to inappropriate mast cell activation and mediator release. Multiorgan involvement in patients can result in significant morbidity and possible mortality. Limited literature exists regarding anesthetic management of patients with MCAS. We report a case of vaginal delivery with neuraxial labor analgesia in a parturient with this condition and highlight the importance of multidisciplinary planning for uneventful outcomes. Stress can trigger life-threatening symptoms, and counseling is important to allay patients’ fears. Optimum medical control, adequate premedication, avoidance of triggers, and preparedness to treat serious mediator effects are key. We review MCAS and discuss anesthetic considerations for patients with this mast cell disorder.
ISSN:2090-6382
2090-6390