Obinutuzumab for treatment of membranous nephropathy in patients positive and negative for the phospholipase A2 receptor antibody: case reports

IntroductionMembranous nephropathy (MN) is a common cause of nephrotic syndrome (NS) in adults. Without treatment, two-thirds of patients with MN develop nonprogressive chronic kidney disease or end-stage renal disease within 10 years. Obinutuzumab (OBZ), which binds to CD20 and leads to a pronounce...

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Bibliographic Details
Main Authors: Jinmeng Wang, Wenfeng Wu, Huiyi Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1561638/full
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