Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations
ObjectiveTo investigate the treatment outcomes of sclerotherapy with pingyangmycin and polidocanol for venous malformations.MethodsThis retrospective study included patients with venous malformations who underwent sclerotherapy between January 2022 and June 2024. Patient demographics, symptoms, trea...
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Frontiers Media S.A.
2025-05-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1565333/full |
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| author | Guanghui He Liping Zhang Lei Guo Aiqiang Han |
| author_facet | Guanghui He Liping Zhang Lei Guo Aiqiang Han |
| author_sort | Guanghui He |
| collection | DOAJ |
| description | ObjectiveTo investigate the treatment outcomes of sclerotherapy with pingyangmycin and polidocanol for venous malformations.MethodsThis retrospective study included patients with venous malformations who underwent sclerotherapy between January 2022 and June 2024. Patient demographics, symptoms, treatment information were gathered from the electronic medical records, and imaging data from the hospital's picture archiving and communication system were reviewed.ResultsA total of 29 patients, composed of 12 males and 17 females, with venous malformations, who underwent 66 procedures during the study period, were analyzed. The lesions were located in the lower limbs in 13 cases, in the upper limbs in 9, in the head and neck in 5, and in the trunk in 2. Twenty-four patients presented with pain, with a median visual analog scale (VAS) score of 4 and the correlation with age was statistically significant. After sclerotherapy, the median VAS score declined to 1, and there was a statistical difference in the overall median VAS score between pre- and post-treatment. According to the evaluation criteria, the treatment response was evaluated as grade 4 in 4 cases, as grade 3 in 17 cases, and as grade 2 in 8 cases; none of the treatment responses was evaluated as grade 1. None of the patients experienced serious adverse reactions.ConclusionSclerotherapy with pingyangmycin and polidocanol is a treatment modality for relieving the clinical symptoms of venous malformations, with good efficacy and few potential risks. |
| format | Article |
| id | doaj-art-145cd062c0ca456cbdfd1b7be8ea378f |
| institution | Kabale University |
| issn | 2296-875X |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj-art-145cd062c0ca456cbdfd1b7be8ea378f2025-08-20T03:52:47ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-05-011210.3389/fsurg.2025.15653331565333Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformationsGuanghui He0Liping Zhang1Lei Guo2Aiqiang Han3Department of Interventional Department, Weifang No. 2 People’s Hospital, Weifang, ChinaDepartment of Interventional Department, Weifang No. 2 People’s Hospital, Weifang, ChinaDepartment of Vascular Anomalies and Interventional Radiology, Children’s Hospital Affiliated to Shandong University, Jinan, ChinaDepartment of Gerontology, Weifang No. 2 People’s Hospital, Weifang, ChinaObjectiveTo investigate the treatment outcomes of sclerotherapy with pingyangmycin and polidocanol for venous malformations.MethodsThis retrospective study included patients with venous malformations who underwent sclerotherapy between January 2022 and June 2024. Patient demographics, symptoms, treatment information were gathered from the electronic medical records, and imaging data from the hospital's picture archiving and communication system were reviewed.ResultsA total of 29 patients, composed of 12 males and 17 females, with venous malformations, who underwent 66 procedures during the study period, were analyzed. The lesions were located in the lower limbs in 13 cases, in the upper limbs in 9, in the head and neck in 5, and in the trunk in 2. Twenty-four patients presented with pain, with a median visual analog scale (VAS) score of 4 and the correlation with age was statistically significant. After sclerotherapy, the median VAS score declined to 1, and there was a statistical difference in the overall median VAS score between pre- and post-treatment. According to the evaluation criteria, the treatment response was evaluated as grade 4 in 4 cases, as grade 3 in 17 cases, and as grade 2 in 8 cases; none of the treatment responses was evaluated as grade 1. None of the patients experienced serious adverse reactions.ConclusionSclerotherapy with pingyangmycin and polidocanol is a treatment modality for relieving the clinical symptoms of venous malformations, with good efficacy and few potential risks.https://www.frontiersin.org/articles/10.3389/fsurg.2025.1565333/fullsclerotherapypingyangmycinpolidocanolvenous malformationtreatment |
| spellingShingle | Guanghui He Liping Zhang Lei Guo Aiqiang Han Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations Frontiers in Surgery sclerotherapy pingyangmycin polidocanol venous malformation treatment |
| title | Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations |
| title_full | Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations |
| title_fullStr | Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations |
| title_full_unstemmed | Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations |
| title_short | Efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations |
| title_sort | efficacy of sclerotherapy with pingyangmycin and polidocanol for venous malformations |
| topic | sclerotherapy pingyangmycin polidocanol venous malformation treatment |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1565333/full |
| work_keys_str_mv | AT guanghuihe efficacyofsclerotherapywithpingyangmycinandpolidocanolforvenousmalformations AT lipingzhang efficacyofsclerotherapywithpingyangmycinandpolidocanolforvenousmalformations AT leiguo efficacyofsclerotherapywithpingyangmycinandpolidocanolforvenousmalformations AT aiqianghan efficacyofsclerotherapywithpingyangmycinandpolidocanolforvenousmalformations |