Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures

A new inorganic-organic hybrid compound, [{Cu(phen)2}2(H4W12O40)], was synthesized, and its crystal structure was determined. The Keggin anion H4W12O404− was grafted with two coordination units {Cu(phen)2}, forming an electrically neutral molecule. The antibacterial activity of several polyoxometala...

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Main Authors: Jingmin Gu, Lei Zhang, Xiaofeng Yuan, Ya-Guang Chen, Xiuzhu Gao, Dong Li
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2018/9342326
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author Jingmin Gu
Lei Zhang
Xiaofeng Yuan
Ya-Guang Chen
Xiuzhu Gao
Dong Li
author_facet Jingmin Gu
Lei Zhang
Xiaofeng Yuan
Ya-Guang Chen
Xiuzhu Gao
Dong Li
author_sort Jingmin Gu
collection DOAJ
description A new inorganic-organic hybrid compound, [{Cu(phen)2}2(H4W12O40)], was synthesized, and its crystal structure was determined. The Keggin anion H4W12O404− was grafted with two coordination units {Cu(phen)2}, forming an electrically neutral molecule. The antibacterial activity of several polyoxometalate compounds with different anionic structures including the new compound was studied. The results show that the compound 1 can inhibit the growth of Enterococcus faecalis FA2 strains and that antibacterial activity of the polyoxometalate compounds is dependent with component elements of POM but is less relative with the anion structures.
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institution OA Journals
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publishDate 2018-01-01
publisher Wiley
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series Bioinorganic Chemistry and Applications
spelling doaj-art-1454a3edb7b34f579e2ace1e8950eae62025-08-20T02:04:52ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2018-01-01201810.1155/2018/93423269342326Synthesis and Antibacterial Activity of Polyoxometalates with Different StructuresJingmin Gu0Lei Zhang1Xiaofeng Yuan2Ya-Guang Chen3Xiuzhu Gao4Dong Li5College of Veterinary Medicine, Jilin University, Changchun 130062, ChinaAnimal Science and Technology College, Jilin Agricultural University, Changchun 130117, ChinaDepartment of Pediatrics, Affiliated Hospital of the Changchun University of Chinese Medicine, Changchun 130021, ChinaKey Laboratory of Polyoxometalates Science of Ministry of Education, Faculty of Chemistry, Northeast Normal University, Changchun 130024, ChinaDepartment of Hepatology, The First Hospital, Jilin University, Changchun 130021, ChinaDepartment of Hepatology, The First Hospital, Jilin University, Changchun 130021, ChinaA new inorganic-organic hybrid compound, [{Cu(phen)2}2(H4W12O40)], was synthesized, and its crystal structure was determined. The Keggin anion H4W12O404− was grafted with two coordination units {Cu(phen)2}, forming an electrically neutral molecule. The antibacterial activity of several polyoxometalate compounds with different anionic structures including the new compound was studied. The results show that the compound 1 can inhibit the growth of Enterococcus faecalis FA2 strains and that antibacterial activity of the polyoxometalate compounds is dependent with component elements of POM but is less relative with the anion structures.http://dx.doi.org/10.1155/2018/9342326
spellingShingle Jingmin Gu
Lei Zhang
Xiaofeng Yuan
Ya-Guang Chen
Xiuzhu Gao
Dong Li
Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
Bioinorganic Chemistry and Applications
title Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
title_full Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
title_fullStr Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
title_full_unstemmed Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
title_short Synthesis and Antibacterial Activity of Polyoxometalates with Different Structures
title_sort synthesis and antibacterial activity of polyoxometalates with different structures
url http://dx.doi.org/10.1155/2018/9342326
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AT yaguangchen synthesisandantibacterialactivityofpolyoxometalateswithdifferentstructures
AT xiuzhugao synthesisandantibacterialactivityofpolyoxometalateswithdifferentstructures
AT dongli synthesisandantibacterialactivityofpolyoxometalateswithdifferentstructures