Methimazole-induced reproductive endocrine system disruption and hepatotoxicity: insights from a Trichogaster trichopterus animal model

Abstract Background Methimazole is commonly prescribed for managing hyperthyroidism, although concerns regarding its reproductive and hepatic adverse effects persist. This study aimed to evaluate the dose-dependent effects of methimazole on reproductive endocrine system function and hepatic integrit...

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Bibliographic Details
Main Authors: Mahdi Ahmadinia, Tahereh Naji, Homayoun Hosseinzadeh Sahafi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Pharmacology and Toxicology
Subjects:
Online Access:https://doi.org/10.1186/s40360-025-00942-y
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