Glucose Sensing in Saliva

Abstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. As such, quantification of glucose levels in body fluids is essential for health monitoring. Blood tes...

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Main Authors: Jacopo Giaretta, Riccardo Zulli, Theja Prabhakar, Ronil J. Rath, Sina Naficy, Sara Spilimbergo, Paul S. Weiss, Syamak Farajikhah, Fariba Dehghani
Format: Article
Language:English
Published: Wiley-VCH 2024-11-01
Series:Advanced Sensor Research
Subjects:
Online Access:https://doi.org/10.1002/adsr.202400065
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author Jacopo Giaretta
Riccardo Zulli
Theja Prabhakar
Ronil J. Rath
Sina Naficy
Sara Spilimbergo
Paul S. Weiss
Syamak Farajikhah
Fariba Dehghani
author_facet Jacopo Giaretta
Riccardo Zulli
Theja Prabhakar
Ronil J. Rath
Sina Naficy
Sara Spilimbergo
Paul S. Weiss
Syamak Farajikhah
Fariba Dehghani
author_sort Jacopo Giaretta
collection DOAJ
description Abstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. As such, quantification of glucose levels in body fluids is essential for health monitoring. Blood tests and, more recently, portable interstitial fluid tests, currently represent the benchmarks for glucose detection. Inconvenient invasive methods such as blood tests pose burdens on both patients and the healthcare system. In this review, noninvasive approaches to measure glucose levels in the human body are discussed, utilizing saliva as an alternative to conventional blood samples. Techniques explored and with the potential to enhance accuracy and their associated challenges are discussed.
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series Advanced Sensor Research
spelling doaj-art-144dab7c14ab4fa784d4b3f2c17ef5a82025-08-20T02:12:47ZengWiley-VCHAdvanced Sensor Research2751-12192024-11-01311n/an/a10.1002/adsr.202400065Glucose Sensing in SalivaJacopo Giaretta0Riccardo Zulli1Theja Prabhakar2Ronil J. Rath3Sina Naficy4Sara Spilimbergo5Paul S. Weiss6Syamak Farajikhah7Fariba Dehghani8School of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaSchool of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaSchool of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaSchool of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaSchool of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaDepartment of Industrial Engineering University of Padova Via Marzolo 9 Padova 35131 ItalyDepartments of Chemistry & Biochemistry Bioengineering and Materials Science & Engineering and California NanoSystems Institute University of California Los Angeles CA 90095 USASchool of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaSchool of Chemical and Biomolecular Engineering The University of Sydney Sydney NSW 2006 AustraliaAbstract Glucose plays critical roles in many human body functions, above all as a source of energy. Abnormal levels of glucose are correlated to different diseases, importantly including diabetes. As such, quantification of glucose levels in body fluids is essential for health monitoring. Blood tests and, more recently, portable interstitial fluid tests, currently represent the benchmarks for glucose detection. Inconvenient invasive methods such as blood tests pose burdens on both patients and the healthcare system. In this review, noninvasive approaches to measure glucose levels in the human body are discussed, utilizing saliva as an alternative to conventional blood samples. Techniques explored and with the potential to enhance accuracy and their associated challenges are discussed.https://doi.org/10.1002/adsr.202400065aptamerbioelectronicelectrochemicalglucosesalivasensor
spellingShingle Jacopo Giaretta
Riccardo Zulli
Theja Prabhakar
Ronil J. Rath
Sina Naficy
Sara Spilimbergo
Paul S. Weiss
Syamak Farajikhah
Fariba Dehghani
Glucose Sensing in Saliva
Advanced Sensor Research
aptamer
bioelectronic
electrochemical
glucose
saliva
sensor
title Glucose Sensing in Saliva
title_full Glucose Sensing in Saliva
title_fullStr Glucose Sensing in Saliva
title_full_unstemmed Glucose Sensing in Saliva
title_short Glucose Sensing in Saliva
title_sort glucose sensing in saliva
topic aptamer
bioelectronic
electrochemical
glucose
saliva
sensor
url https://doi.org/10.1002/adsr.202400065
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AT thejaprabhakar glucosesensinginsaliva
AT roniljrath glucosesensinginsaliva
AT sinanaficy glucosesensinginsaliva
AT saraspilimbergo glucosesensinginsaliva
AT paulsweiss glucosesensinginsaliva
AT syamakfarajikhah glucosesensinginsaliva
AT faribadehghani glucosesensinginsaliva