A Retrospective Analysis of Polymer Selection Using Solvent Casting: Formulation and DoE Optimization of the Amorphous Solid Dispersion of Amoxicillin Trihydrate by a Spray Drying Method

A Retrospective Analysis of Polymer Selection Using Solvent Casting: Formulation and DoE Optimization of the Amorphous Solid Dispersion of Amoxicillin Trihydrate by a Spray Drying Method

Background. Amoxicillin trihydrate possesses poor solubility, compressibility, and flow behavior. Amorphous solid dispersion prepared by spray drying could solve all three problems at the same time. Objective. To prepare amorphous solid dispersion after screening of polymers by solvent casting metho...

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Bibliographic Details
Main Authors: Chetan Borkhataria, Hardik Chauhan, Bhargavi Mistry, Manisha Kalaria, Rachana Katbamana, Kalpesh Patel
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Chemical Engineering
Online Access:http://dx.doi.org/10.1155/2024/8734695
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