A Giant Primary Mediastinal Teratocarcinoma in a Male Adult
Germ cell tumors (GCTs) arise along the midline, in which 50-70% of extragonadal GCTs occur in the mediastinum. Malignant GCTs are more common in males, while benign GCTs occur equally in both males and females. This report presents a case of a giant primary mediastinal nonseminomatous GCT resected...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2019/7123241 |
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| author | Muneera Al-Khalifa Sara Alsaad Habib Al-Tareef Zaid Arekat Abdulla Darwish |
| author_facet | Muneera Al-Khalifa Sara Alsaad Habib Al-Tareef Zaid Arekat Abdulla Darwish |
| author_sort | Muneera Al-Khalifa |
| collection | DOAJ |
| description | Germ cell tumors (GCTs) arise along the midline, in which 50-70% of extragonadal GCTs occur in the mediastinum. Malignant GCTs are more common in males, while benign GCTs occur equally in both males and females. This report presents a case of a giant primary mediastinal nonseminomatous GCT resected from a 35-year-old male who presented with dyspnoea and tightness in the chest. Thorough investigations including a chest MRI were done. It showed a 21×19×15 cm tumor. Thus, surgical resection of the tumor through a midline sternotomy was done. Histopathological analysis diagnosed the tumor as a primary mediastinal teratocarcinoma with a sarcomatous component. Eighteen-month follow-up showed no tumor recurrence. Mediastinal teratocarcinoma is a rare and life-threatening germ cell tumor. Studies recommend the use of chemotherapy prior to resection as an important step in its management. Close and regular follow-up postsurgical resection is advised. |
| format | Article |
| id | doaj-art-143bd65db4094f9487fec079ea70ce3f |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-143bd65db4094f9487fec079ea70ce3f2025-08-20T03:54:33ZengWileyCase Reports in Surgery2090-69002090-69192019-01-01201910.1155/2019/71232417123241A Giant Primary Mediastinal Teratocarcinoma in a Male AdultMuneera Al-Khalifa0Sara Alsaad1Habib Al-Tareef2Zaid Arekat3Abdulla Darwish4RCSI-MUB, Busaiteen, BahrainDepartment of Pathology, Bahrain Defense Force Hospital, Riffa, BahrainMohammed Bin Khalifa Cardiac Center, Bahrain Defense Force Hospital, Riffa, BahrainMohammed Bin Khalifa Cardiac Center, Bahrain Defense Force Hospital, Riffa, BahrainDepartment of Pathology, Bahrain Defense Force Hospital, Riffa, BahrainGerm cell tumors (GCTs) arise along the midline, in which 50-70% of extragonadal GCTs occur in the mediastinum. Malignant GCTs are more common in males, while benign GCTs occur equally in both males and females. This report presents a case of a giant primary mediastinal nonseminomatous GCT resected from a 35-year-old male who presented with dyspnoea and tightness in the chest. Thorough investigations including a chest MRI were done. It showed a 21×19×15 cm tumor. Thus, surgical resection of the tumor through a midline sternotomy was done. Histopathological analysis diagnosed the tumor as a primary mediastinal teratocarcinoma with a sarcomatous component. Eighteen-month follow-up showed no tumor recurrence. Mediastinal teratocarcinoma is a rare and life-threatening germ cell tumor. Studies recommend the use of chemotherapy prior to resection as an important step in its management. Close and regular follow-up postsurgical resection is advised.http://dx.doi.org/10.1155/2019/7123241 |
| spellingShingle | Muneera Al-Khalifa Sara Alsaad Habib Al-Tareef Zaid Arekat Abdulla Darwish A Giant Primary Mediastinal Teratocarcinoma in a Male Adult Case Reports in Surgery |
| title | A Giant Primary Mediastinal Teratocarcinoma in a Male Adult |
| title_full | A Giant Primary Mediastinal Teratocarcinoma in a Male Adult |
| title_fullStr | A Giant Primary Mediastinal Teratocarcinoma in a Male Adult |
| title_full_unstemmed | A Giant Primary Mediastinal Teratocarcinoma in a Male Adult |
| title_short | A Giant Primary Mediastinal Teratocarcinoma in a Male Adult |
| title_sort | giant primary mediastinal teratocarcinoma in a male adult |
| url | http://dx.doi.org/10.1155/2019/7123241 |
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