Human V4 size predicts crowding distance

Abstract Visual recognition is limited by both object size (acuity) and spacing. The spacing limit, called “crowding”, is the failure to recognize an object in the presence of other objects. Here, we take advantage of individual differences in crowding to investigate its biological basis. Crowding d...

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Main Authors: Jan W. Kurzawski, Brenda S. Qiu, Najib J. Majaj, Noah C. Benson, Denis G. Pelli, Jonathan Winawer
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59101-w
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author Jan W. Kurzawski
Brenda S. Qiu
Najib J. Majaj
Noah C. Benson
Denis G. Pelli
Jonathan Winawer
author_facet Jan W. Kurzawski
Brenda S. Qiu
Najib J. Majaj
Noah C. Benson
Denis G. Pelli
Jonathan Winawer
author_sort Jan W. Kurzawski
collection DOAJ
description Abstract Visual recognition is limited by both object size (acuity) and spacing. The spacing limit, called “crowding”, is the failure to recognize an object in the presence of other objects. Here, we take advantage of individual differences in crowding to investigate its biological basis. Crowding distance, the minimum object spacing needed for recognition, varies 2-fold among healthy adults. We test the conjecture that this variation in psychophysical crowding distance is due to variation in cortical map size. To test this, we make paired measurements of brain and behavior in 49 observers. We use psychophysics to measure crowding distance and calculate λ, the number of letters that fit into each observer’s visual field without crowding. In the same observers, we use functional magnetic resonance imaging (fMRI) to measure the surface area A of retinotopic maps V1, V2, V3, and V4. Across observers, λ is proportional to the surface area of V4 but is uncorrelated with the surface area of V1 to V3. The proportional relationship of λ to area of V4 indicates conservation of cortical crowding distance across individuals: letters can be recognized if they are spaced by at least 1.4 mm on the V4 map, irrespective of map size and psychophysical crowding distance. We conclude that the size of V4 predicts the spacing limit of visual perception.
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spelling doaj-art-142e275b7d88420aaf2f75c199dd9f212025-08-20T04:02:56ZengNature PortfolioNature Communications2041-17232025-04-0116111110.1038/s41467-025-59101-wHuman V4 size predicts crowding distanceJan W. Kurzawski0Brenda S. Qiu1Najib J. Majaj2Noah C. Benson3Denis G. Pelli4Jonathan Winawer5Department of Psychology, New York UniversityDepartment of Psychology, University of WashingtonCenter for Neural Science, New York UniversityeScience Institute, University of WashingtonDepartment of Psychology, New York UniversityDepartment of Psychology, New York UniversityAbstract Visual recognition is limited by both object size (acuity) and spacing. The spacing limit, called “crowding”, is the failure to recognize an object in the presence of other objects. Here, we take advantage of individual differences in crowding to investigate its biological basis. Crowding distance, the minimum object spacing needed for recognition, varies 2-fold among healthy adults. We test the conjecture that this variation in psychophysical crowding distance is due to variation in cortical map size. To test this, we make paired measurements of brain and behavior in 49 observers. We use psychophysics to measure crowding distance and calculate λ, the number of letters that fit into each observer’s visual field without crowding. In the same observers, we use functional magnetic resonance imaging (fMRI) to measure the surface area A of retinotopic maps V1, V2, V3, and V4. Across observers, λ is proportional to the surface area of V4 but is uncorrelated with the surface area of V1 to V3. The proportional relationship of λ to area of V4 indicates conservation of cortical crowding distance across individuals: letters can be recognized if they are spaced by at least 1.4 mm on the V4 map, irrespective of map size and psychophysical crowding distance. We conclude that the size of V4 predicts the spacing limit of visual perception.https://doi.org/10.1038/s41467-025-59101-w
spellingShingle Jan W. Kurzawski
Brenda S. Qiu
Najib J. Majaj
Noah C. Benson
Denis G. Pelli
Jonathan Winawer
Human V4 size predicts crowding distance
Nature Communications
title Human V4 size predicts crowding distance
title_full Human V4 size predicts crowding distance
title_fullStr Human V4 size predicts crowding distance
title_full_unstemmed Human V4 size predicts crowding distance
title_short Human V4 size predicts crowding distance
title_sort human v4 size predicts crowding distance
url https://doi.org/10.1038/s41467-025-59101-w
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