Keratoconus with two consecutive re-emergences: a case report
Abstract Background Keratoconus is a common disease in clinical practice, and deep anterior lamellar keratoplasty(DALK) is a conventional treatment for keratoconus, which is effective and not easy to recur after surgery. Case presentation The author presents a rare case report involving a 21-year-ol...
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| Language: | English |
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BMC
2025-02-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-025-03877-4 |
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| author | Peicheng Zhang Yanchao Wu Lixiao Ma Dong Wang |
| author_facet | Peicheng Zhang Yanchao Wu Lixiao Ma Dong Wang |
| author_sort | Peicheng Zhang |
| collection | DOAJ |
| description | Abstract Background Keratoconus is a common disease in clinical practice, and deep anterior lamellar keratoplasty(DALK) is a conventional treatment for keratoconus, which is effective and not easy to recur after surgery. Case presentation The author presents a rare case report involving a 21-year-old patient with Consecutive re-emergences of Keratoconus. He underwent DALK for keratoconus in his left eye in 2012 and experienced re-emergence 3 years later, followed by a second deep lamellar keratoplasty in the same year. In 2019, the patient experienced re-emergence of keratoconus and underwent a third deep lamellar keratoplasty in the same eye. Genetic testing was performed, and no abnormal genes were identified. Postoperative follow-up emphasized the management of chronic allergic conjunctivitis (CAC) and the correction of eye-rubbing habits. To date, he has not experienced any further re-emergence. Conclusions Keratoconus is a complex disorder with a multifaceted etiology and pathogenesis, including genetic, environmental, biomechanical, and cellular factors. Its treatment usually requires multiple considerations, including the choice of surgical methods, anti-inflammatory therapy, and correction of eye rubbing habits to guide patients for subsequent treatment interventions. |
| format | Article |
| id | doaj-art-142d94d9a0c34ac795311fd60e2c26b0 |
| institution | Kabale University |
| issn | 1471-2415 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj-art-142d94d9a0c34ac795311fd60e2c26b02025-02-09T12:26:16ZengBMCBMC Ophthalmology1471-24152025-02-012511510.1186/s12886-025-03877-4Keratoconus with two consecutive re-emergences: a case reportPeicheng Zhang0Yanchao Wu1Lixiao Ma2Dong Wang3Hebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Clinical Medical Research Center for Ocular Diseases, Hebei Eye Hospital, Xiangdu DistrictHebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Clinical Medical Research Center for Ocular Diseases, Hebei Eye Hospital, Xiangdu DistrictHebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Clinical Medical Research Center for Ocular Diseases, Hebei Eye Hospital, Xiangdu DistrictHebei Provincial Key Laboratory of Ophthalmology, Hebei Provincial Clinical Medical Research Center for Ocular Diseases, Hebei Eye Hospital, Xiangdu DistrictAbstract Background Keratoconus is a common disease in clinical practice, and deep anterior lamellar keratoplasty(DALK) is a conventional treatment for keratoconus, which is effective and not easy to recur after surgery. Case presentation The author presents a rare case report involving a 21-year-old patient with Consecutive re-emergences of Keratoconus. He underwent DALK for keratoconus in his left eye in 2012 and experienced re-emergence 3 years later, followed by a second deep lamellar keratoplasty in the same year. In 2019, the patient experienced re-emergence of keratoconus and underwent a third deep lamellar keratoplasty in the same eye. Genetic testing was performed, and no abnormal genes were identified. Postoperative follow-up emphasized the management of chronic allergic conjunctivitis (CAC) and the correction of eye-rubbing habits. To date, he has not experienced any further re-emergence. Conclusions Keratoconus is a complex disorder with a multifaceted etiology and pathogenesis, including genetic, environmental, biomechanical, and cellular factors. Its treatment usually requires multiple considerations, including the choice of surgical methods, anti-inflammatory therapy, and correction of eye rubbing habits to guide patients for subsequent treatment interventions.https://doi.org/10.1186/s12886-025-03877-4KeratoconusRecurrent keratoconusDeep anterior lamellar keratoplastyChronic allergic conjunctivitisEye-rubbing |
| spellingShingle | Peicheng Zhang Yanchao Wu Lixiao Ma Dong Wang Keratoconus with two consecutive re-emergences: a case report BMC Ophthalmology Keratoconus Recurrent keratoconus Deep anterior lamellar keratoplasty Chronic allergic conjunctivitis Eye-rubbing |
| title | Keratoconus with two consecutive re-emergences: a case report |
| title_full | Keratoconus with two consecutive re-emergences: a case report |
| title_fullStr | Keratoconus with two consecutive re-emergences: a case report |
| title_full_unstemmed | Keratoconus with two consecutive re-emergences: a case report |
| title_short | Keratoconus with two consecutive re-emergences: a case report |
| title_sort | keratoconus with two consecutive re emergences a case report |
| topic | Keratoconus Recurrent keratoconus Deep anterior lamellar keratoplasty Chronic allergic conjunctivitis Eye-rubbing |
| url | https://doi.org/10.1186/s12886-025-03877-4 |
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