Overcoming chemoresistance in mucinous adenocarcinoma: the impact of tumor microenvironment and genetic alterations

Background: Mucinous adenocarcinoma (MAC) is a rare, aggressive subtype of adenocarcinoma, distinguished by excessive extracellular mucin production. This feature impairs drug penetration and contributes to poor chemotherapy response and chemoresistance. Genetic mutations (e.g., KRAS, BRAF, PI3K/AKT...

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Bibliographic Details
Main Authors: Kaniga Pandi, Binoy Varghese Cheriyan, Vishali Ramesh, Sowparnika Murugavel, Jaya Surya Venkatesan
Format: Article
Language:English
Published: Creative Pharma Assent 2025-06-01
Series:Journal of Applied Pharmaceutical Research
Subjects:
Online Access:https://japtronline.com/index.php/joapr/article/view/1032
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