Evaluation of hypoxia-inducible factor-1α and urine non-transferrin-bound iron concentrations in cats with chronic kidney disease

Evaluation of hypoxia-inducible factor-1α and urine non-transferrin-bound iron concentrations in cats with chronic kidney disease

IntroductionHypoxia-inducible factors (HIF) regulate gene transcription, which aids hypoxia adaptation while promoting renal fibrosis. Non-transferrin-bound iron (NTBI) is a catalytic form of iron that can lead to oxidative damage. However, NTBI in cat biofluids has rarely been evaluated.AimsWe asse...

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Bibliographic Details
Main Authors: Chien-Hui Chen, Wei-Li Hsu, Pei-Shiue Jason Tsai, Chun-Fu Lai, Meng-Ting Wu, Ya-Jane Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Veterinary Science
Subjects:
HIF
NTBI
CKD
noninvasive biomarkers
renal disease
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2024.1482998/full
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