Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year

Objectives: This study investigated the changes of lower urinary tract function after robot-assisted radical prostatectomy (RaRP) with 1-year urodynamic follow-up. Materials and Methods: Clinically localized prostate cancer patients receiving RaRP were prospectively enrolled. We analyzed their clini...

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Main Authors: Yuan-Hong Jiang, Hann-Chorng Kuo
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Tzu Chi Medical Journal
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Online Access:http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=2;spage=158;epage=164;aulast=Jiang
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author Yuan-Hong Jiang
Hann-Chorng Kuo
author_facet Yuan-Hong Jiang
Hann-Chorng Kuo
author_sort Yuan-Hong Jiang
collection DOAJ
description Objectives: This study investigated the changes of lower urinary tract function after robot-assisted radical prostatectomy (RaRP) with 1-year urodynamic follow-up. Materials and Methods: Clinically localized prostate cancer patients receiving RaRP were prospectively enrolled. We analyzed their clinical symptoms, stress urinary incontinence (SUI) and urge urinary incontinence (UUI) status, and videourodynamic studies (VUDSs) during the postoperative 1st year. Results: In total, 74 patients were enrolled with a mean age of 69.4 ± 8.1 years, a mean total prostate volume of 34.7 ± 15.9 mL, a ≥pT3 stage proportion of 37.8%, and a positive surgical margin rate of 18.9%. The International Prostate Symptom Score significantly reduced from 7.3 ± 6.0 before surgery to 4.1 ± 4.1 at postoperative 1 year. Significantly increased full sensation, reduced detrusor voiding pressure, increased maximal urinary flow rate, and decreased bladder outlet obstruction index were noted at 1-year VUDS follow-up. The changes of VUDS parameters were significantly different between the patients with and without preoperative bladder outlet obstruction. At postoperative 1 year, 8.1% and 6.8% of patients experienced SUI and UUI, respectively. In multivariate analysis, the factors of T stage ≥3, preoperative detrusor overactivity (DO), and positive surgical margin were the independent predictors of immediate SUI and SUI at 3 and 12 months, respectively. Conclusion: During the 1st year after RaRP, patients experienced significant changes of lower urinary tract function demonstrated in VUDS with the improvement in clinical symptoms. Factors of T stage ≥3, preoperative DO, and positive surgical margin were the predictors of postoperative SUI.
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spelling doaj-art-141d460f29224211a192c5a4bee9ef622025-08-20T03:17:25ZengWolters Kluwer Medknow PublicationsTzu Chi Medical Journal1016-31902223-89562023-01-0135215816410.4103/tcmj.tcmj_96_22Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 yearYuan-Hong JiangHann-Chorng KuoObjectives: This study investigated the changes of lower urinary tract function after robot-assisted radical prostatectomy (RaRP) with 1-year urodynamic follow-up. Materials and Methods: Clinically localized prostate cancer patients receiving RaRP were prospectively enrolled. We analyzed their clinical symptoms, stress urinary incontinence (SUI) and urge urinary incontinence (UUI) status, and videourodynamic studies (VUDSs) during the postoperative 1st year. Results: In total, 74 patients were enrolled with a mean age of 69.4 ± 8.1 years, a mean total prostate volume of 34.7 ± 15.9 mL, a ≥pT3 stage proportion of 37.8%, and a positive surgical margin rate of 18.9%. The International Prostate Symptom Score significantly reduced from 7.3 ± 6.0 before surgery to 4.1 ± 4.1 at postoperative 1 year. Significantly increased full sensation, reduced detrusor voiding pressure, increased maximal urinary flow rate, and decreased bladder outlet obstruction index were noted at 1-year VUDS follow-up. The changes of VUDS parameters were significantly different between the patients with and without preoperative bladder outlet obstruction. At postoperative 1 year, 8.1% and 6.8% of patients experienced SUI and UUI, respectively. In multivariate analysis, the factors of T stage ≥3, preoperative detrusor overactivity (DO), and positive surgical margin were the independent predictors of immediate SUI and SUI at 3 and 12 months, respectively. Conclusion: During the 1st year after RaRP, patients experienced significant changes of lower urinary tract function demonstrated in VUDS with the improvement in clinical symptoms. Factors of T stage ≥3, preoperative DO, and positive surgical margin were the predictors of postoperative SUI.http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=2;spage=158;epage=164;aulast=Jianglower urinary tract functionpostprostatectomy incontinencerobotic-assisted radical prostatectomyvideourodynamic study
spellingShingle Yuan-Hong Jiang
Hann-Chorng Kuo
Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year
Tzu Chi Medical Journal
lower urinary tract function
postprostatectomy incontinence
robotic-assisted radical prostatectomy
videourodynamic study
title Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year
title_full Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year
title_fullStr Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year
title_full_unstemmed Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year
title_short Changes of lower urinary tract function after robot-assisted radical prostatectomy: An urodynamic follow-up within 1 year
title_sort changes of lower urinary tract function after robot assisted radical prostatectomy an urodynamic follow up within 1 year
topic lower urinary tract function
postprostatectomy incontinence
robotic-assisted radical prostatectomy
videourodynamic study
url http://www.tcmjmed.com/article.asp?issn=1016-3190;year=2023;volume=35;issue=2;spage=158;epage=164;aulast=Jiang
work_keys_str_mv AT yuanhongjiang changesoflowerurinarytractfunctionafterrobotassistedradicalprostatectomyanurodynamicfollowupwithin1year
AT hannchorngkuo changesoflowerurinarytractfunctionafterrobotassistedradicalprostatectomyanurodynamicfollowupwithin1year