Plasma plasminogen levels in early respiratory distress syndrome

The serum plasminogen status in 35 preterm infants with or without respiratory distress syndrome (RDS) was determined in the first few hours of life. Blood samples for plasminogen testing (Synthetic chromogenic substrate method; Stachorm PLG. Diagnostica Stago) were obtained from a peripheral...

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Main Authors: M Yurdakök, S Yiğit, B Gürakan, S Dündar, S Kirazli
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 1996-04-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/3473
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author M Yurdakök
S Yiğit
B Gürakan
S Dündar
S Kirazli
author_facet M Yurdakök
S Yiğit
B Gürakan
S Dündar
S Kirazli
author_sort M Yurdakök
collection DOAJ
description The serum plasminogen status in 35 preterm infants with or without respiratory distress syndrome (RDS) was determined in the first few hours of life. Blood samples for plasminogen testing (Synthetic chromogenic substrate method; Stachorm PLG. Diagnostica Stago) were obtained from a peripheral vein within six hours after birth. Among 35 infants, 20 infants who were in stable clinical condition served as the control group. Fifteen developed RDS with clinical, laboratory and radiological findings. The mean plasma plasminogen levels were found to be similar in the two groups (p > 0.05 by Mann-Whitney U test). These findings are discussed along with our previous findings showing normal tissue plasminogen activator (tPA) but lower D-dimer and higher plasminogen activator inhibitor (PAI) levels within the first few hours of life in preterm infants who later developed RDS compared to the control group.
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id doaj-art-141cea50a4814582b1997bc04005af8d
institution DOAJ
issn 0041-4301
2791-6421
language English
publishDate 1996-04-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-141cea50a4814582b1997bc04005af8d2025-08-20T02:59:46ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64211996-04-01382Plasma plasminogen levels in early respiratory distress syndromeM Yurdakök0S YiğitB GürakanS DündarS KirazliDepartment of Pediatrics, Hacettepe University Faculty of Medicine, Ankara. The serum plasminogen status in 35 preterm infants with or without respiratory distress syndrome (RDS) was determined in the first few hours of life. Blood samples for plasminogen testing (Synthetic chromogenic substrate method; Stachorm PLG. Diagnostica Stago) were obtained from a peripheral vein within six hours after birth. Among 35 infants, 20 infants who were in stable clinical condition served as the control group. Fifteen developed RDS with clinical, laboratory and radiological findings. The mean plasma plasminogen levels were found to be similar in the two groups (p > 0.05 by Mann-Whitney U test). These findings are discussed along with our previous findings showing normal tissue plasminogen activator (tPA) but lower D-dimer and higher plasminogen activator inhibitor (PAI) levels within the first few hours of life in preterm infants who later developed RDS compared to the control group. https://turkjpediatr.org/article/view/3473
spellingShingle M Yurdakök
S Yiğit
B Gürakan
S Dündar
S Kirazli
Plasma plasminogen levels in early respiratory distress syndrome
The Turkish Journal of Pediatrics
title Plasma plasminogen levels in early respiratory distress syndrome
title_full Plasma plasminogen levels in early respiratory distress syndrome
title_fullStr Plasma plasminogen levels in early respiratory distress syndrome
title_full_unstemmed Plasma plasminogen levels in early respiratory distress syndrome
title_short Plasma plasminogen levels in early respiratory distress syndrome
title_sort plasma plasminogen levels in early respiratory distress syndrome
url https://turkjpediatr.org/article/view/3473
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AT syigit plasmaplasminogenlevelsinearlyrespiratorydistresssyndrome
AT bgurakan plasmaplasminogenlevelsinearlyrespiratorydistresssyndrome
AT sdundar plasmaplasminogenlevelsinearlyrespiratorydistresssyndrome
AT skirazli plasmaplasminogenlevelsinearlyrespiratorydistresssyndrome