Severe Cases of Tick-Borne Encephalitis in Northeastern Poland

Tick-borne encephalitis (TBE) is the most prevalent viral infection of the central nervous system (CNS) in Poland. The disease is characterized by the presence of two stages. The first phase, called the viremic stage, presents with flu-like symptoms, while the second stage of TBE is characterized by...

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Main Authors: Justyna Adamczuk, Magdalena Chlabicz, Natalia Koda, Maciej Kondrusik, Joanna Zajkowska, Piotr Czupryna, Anna Moniuszko-Malinowska
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pathogens
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Online Access:https://www.mdpi.com/2076-0817/14/1/7
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author Justyna Adamczuk
Magdalena Chlabicz
Natalia Koda
Maciej Kondrusik
Joanna Zajkowska
Piotr Czupryna
Anna Moniuszko-Malinowska
author_facet Justyna Adamczuk
Magdalena Chlabicz
Natalia Koda
Maciej Kondrusik
Joanna Zajkowska
Piotr Czupryna
Anna Moniuszko-Malinowska
author_sort Justyna Adamczuk
collection DOAJ
description Tick-borne encephalitis (TBE) is the most prevalent viral infection of the central nervous system (CNS) in Poland. The disease is characterized by the presence of two stages. The first phase, called the viremic stage, presents with flu-like symptoms, while the second stage of TBE is characterized by damage to the nervous system and may follow a severe and dramatic course. The aim of this paper is to increase the awareness of the potential sequelae after TBE. In this study, we report cases of severe TBE in 36-year-old and 57-year-old female patients. The outcome of TBE varies from patient to patient, but there are some factors that can help to predict the severity of TBE infection. The risk factors presented in these patients were as follows: the monophasic course of TBE, high pleocytosis in cerebrospinal fluid (CSF) and older age. Both of our patients were not vaccinated despite the World Health Organization’s (WHO’s) recommendations. Both patients had no history of travel outside their region of residence prior to the onset of illness. The few risk factors shown in our patients and the serious sequelae of the disease may indicate the need to test patients for possible gene mutations.
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issn 2076-0817
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series Pathogens
spelling doaj-art-141a8ae418104e0793a9a76e8f57709e2025-01-24T13:44:34ZengMDPI AGPathogens2076-08172024-12-01141710.3390/pathogens14010007Severe Cases of Tick-Borne Encephalitis in Northeastern PolandJustyna Adamczuk0Magdalena Chlabicz1Natalia Koda2Maciej Kondrusik3Joanna Zajkowska4Piotr Czupryna5Anna Moniuszko-Malinowska6Department of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandStudents’ Scientific Club at the Department of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandStudents’ Scientific Club at the Department of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandDepartment of Infectious Diseases and Neuroinfections, Medical University of Bialystok, 15-540 Bialystok, PolandTick-borne encephalitis (TBE) is the most prevalent viral infection of the central nervous system (CNS) in Poland. The disease is characterized by the presence of two stages. The first phase, called the viremic stage, presents with flu-like symptoms, while the second stage of TBE is characterized by damage to the nervous system and may follow a severe and dramatic course. The aim of this paper is to increase the awareness of the potential sequelae after TBE. In this study, we report cases of severe TBE in 36-year-old and 57-year-old female patients. The outcome of TBE varies from patient to patient, but there are some factors that can help to predict the severity of TBE infection. The risk factors presented in these patients were as follows: the monophasic course of TBE, high pleocytosis in cerebrospinal fluid (CSF) and older age. Both of our patients were not vaccinated despite the World Health Organization’s (WHO’s) recommendations. Both patients had no history of travel outside their region of residence prior to the onset of illness. The few risk factors shown in our patients and the serious sequelae of the disease may indicate the need to test patients for possible gene mutations.https://www.mdpi.com/2076-0817/14/1/7tick-borne encephalitisviral infectionmeningoencephalitissevere case
spellingShingle Justyna Adamczuk
Magdalena Chlabicz
Natalia Koda
Maciej Kondrusik
Joanna Zajkowska
Piotr Czupryna
Anna Moniuszko-Malinowska
Severe Cases of Tick-Borne Encephalitis in Northeastern Poland
Pathogens
tick-borne encephalitis
viral infection
meningoencephalitis
severe case
title Severe Cases of Tick-Borne Encephalitis in Northeastern Poland
title_full Severe Cases of Tick-Borne Encephalitis in Northeastern Poland
title_fullStr Severe Cases of Tick-Borne Encephalitis in Northeastern Poland
title_full_unstemmed Severe Cases of Tick-Borne Encephalitis in Northeastern Poland
title_short Severe Cases of Tick-Borne Encephalitis in Northeastern Poland
title_sort severe cases of tick borne encephalitis in northeastern poland
topic tick-borne encephalitis
viral infection
meningoencephalitis
severe case
url https://www.mdpi.com/2076-0817/14/1/7
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AT nataliakoda severecasesoftickborneencephalitisinnortheasternpoland
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