Mutual suppression between mutations in the Dictyostelium Greenbeard pathway restores wild-type development

Mutual suppression between mutations in the Dictyostelium Greenbeard pathway restores wild-type development

Abstract Background The Dictyostelium greenbeard pathway is mediated by two polymorphic transmembrane proteins, the TgrC1 ligand and the TgrB1 receptor. These proteins mediate allorecognition, altruism, and the developmental transition to multicellularity. A genetic suppressor screen revealed activa...

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Bibliographic Details
Main Authors: Mariko Katoh-Kurasawa, Lena Trnovec, Peter Lehmann, Blaž Zupan, Gad Shaulsky
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Genomics
Subjects:
Mutual suppression
Greenbeard pathway
Dictyostelium allorecognition
Dictyostelium development
Transcriptome phenotyping
Online Access:https://doi.org/10.1186/s12864-025-11745-0
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