Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador
Introduction: Acinetobacter baumannii (ABA) is an important opportunistic pathogen associated with high mortality rates in intensive care units (ICUs). An outbreak in the ICU of a secondary-level hospital in Quito, Ecuador, occurred during April and May 2015 and was successfully controlled. Methodo...
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The Journal of Infection in Developing Countries
2016-12-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/7544 |
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| author | Monica Cartelle Gestal Jeannete Zurita Gabriela Gualpa Cecibel Gonzalez Ariane Paz y Mino |
| author_facet | Monica Cartelle Gestal Jeannete Zurita Gabriela Gualpa Cecibel Gonzalez Ariane Paz y Mino |
| author_sort | Monica Cartelle Gestal |
| collection | DOAJ |
| description | Introduction: Acinetobacter baumannii (ABA) is an important opportunistic pathogen associated with high mortality rates in intensive care units (ICUs). An outbreak in the ICU of a secondary-level hospital in Quito, Ecuador, occurred during April and May 2015 and was successfully controlled.
Methodology: Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) and repetitive element palindromic (REP)-PCR was conducted on all isolates recovered from patients, as well as environmental samples, to confirm the presence of an outbreak. A case-control study was conducted by comparing the clinical histories of the affected patients and of control patients present in the ICU during the outbreak period who did not present a positive culture for ABA.
Results: Five patients were infected and two were colonized with the same clonal strain of ABA, which was also identified on the stethoscope and a monitor associated with an isolation room. Statistical analysis of case histories did not identify any additional risk factors, but the outbreak was initiated by one patient in the isolation room of the ICU who was infected with the outbreak strain. All patients who ocupied that room after the index case tested positive for at least one culture of ABA. The outbreak strain was found on the stethoscope, and a subclone was found on the monitor of that room.
Conclusion: Having access to basic equipment will enable well-trained professionals to rapidly detect and initiate the control process of an outbreak, saving lives and money spent on nosocomial infection treatments.
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| format | Article |
| id | doaj-art-140e85315c544ecd9ad2225eb946ceaa |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-140e85315c544ecd9ad2225eb946ceaa2025-08-20T03:48:46ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802016-12-01101210.3855/jidc.7544Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, EcuadorMonica Cartelle Gestal0Jeannete Zurita1Gabriela Gualpa2Cecibel Gonzalez3Ariane Paz y Mino4Zurita and Zurita Laboratories, Avenida de la Prensa, Quito, EcuadorZurita and Zurita Laboratories, Avenida de la Prensa, Quito, EcuadorFacultad de Medicina, Pontificia Universidad Católica del Ecuador, Quito, EcuadorZurita and Zurita Laboratories, Avenida de la Prensa, Quito, EcuadorZurita and Zurita Laboratories, Avenida de la Prensa, Quito, EcuadorIntroduction: Acinetobacter baumannii (ABA) is an important opportunistic pathogen associated with high mortality rates in intensive care units (ICUs). An outbreak in the ICU of a secondary-level hospital in Quito, Ecuador, occurred during April and May 2015 and was successfully controlled. Methodology: Enterobacterial repetitive intergenic consensus polymerase chain reaction (ERIC-PCR) and repetitive element palindromic (REP)-PCR was conducted on all isolates recovered from patients, as well as environmental samples, to confirm the presence of an outbreak. A case-control study was conducted by comparing the clinical histories of the affected patients and of control patients present in the ICU during the outbreak period who did not present a positive culture for ABA. Results: Five patients were infected and two were colonized with the same clonal strain of ABA, which was also identified on the stethoscope and a monitor associated with an isolation room. Statistical analysis of case histories did not identify any additional risk factors, but the outbreak was initiated by one patient in the isolation room of the ICU who was infected with the outbreak strain. All patients who ocupied that room after the index case tested positive for at least one culture of ABA. The outbreak strain was found on the stethoscope, and a subclone was found on the monitor of that room. Conclusion: Having access to basic equipment will enable well-trained professionals to rapidly detect and initiate the control process of an outbreak, saving lives and money spent on nosocomial infection treatments. https://jidc.org/index.php/journal/article/view/7544outbreakAcinetobacter baumanniinosocomial infectionscontrolABA |
| spellingShingle | Monica Cartelle Gestal Jeannete Zurita Gabriela Gualpa Cecibel Gonzalez Ariane Paz y Mino Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador Journal of Infection in Developing Countries outbreak Acinetobacter baumannii nosocomial infections control ABA |
| title | Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador |
| title_full | Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador |
| title_fullStr | Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador |
| title_full_unstemmed | Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador |
| title_short | Early detection and control of an Acinetobacter baumannii multi-resistant outbreak in a hospital in Quito, Ecuador |
| title_sort | early detection and control of an acinetobacter baumannii multi resistant outbreak in a hospital in quito ecuador |
| topic | outbreak Acinetobacter baumannii nosocomial infections control ABA |
| url | https://jidc.org/index.php/journal/article/view/7544 |
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