Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

Abstract Mitofusin 1 (MFN1) plays a crucial role in mitochondrial fusion and oocyte development. However, its function in preimplantation embryonic development and its potential involvement in epigenetic regulation remain poorly understood. In this study, it is shown that MFN1 interacts with PADI6,...

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Bibliographic Details
Main Authors: Xiao‐yan Shi, Yu Tian, Yu‐fan Wang, Yi‐ran Zhang, Ying Yin, Qing Tian, Lei Li, Bing‐xin Ma, Ximiao He, Li‐quan Zhou
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Advanced Science
Subjects:
cytoplasmic lattice
H3.3
MFN1
preimplantation
zygotic genome activation
Online Access:https://doi.org/10.1002/advs.202414985
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