The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia

Background: Orofacial clefts are considered one of the most common birth defects and are frequently associated with other malformations. Congenital heart disease is one of the most prevalent congenital malformation. Objective: To investigate the prevalence of congenital heart diseases associated wit...

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Main Authors: Ziyad AlHammad, Ihab Suliman, Sami Alotaibi, Hourya Alnofaie, Waad Alsaadi, Sarah Alhusseini, Ghadah Aldakheel, Noura Alsubaie
Format: Article
Language:English
Published: Springer 2021-03-01
Series:Saudi Dental Journal
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Online Access:http://www.sciencedirect.com/science/article/pii/S1013905219308387
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author Ziyad AlHammad
Ihab Suliman
Sami Alotaibi
Hourya Alnofaie
Waad Alsaadi
Sarah Alhusseini
Ghadah Aldakheel
Noura Alsubaie
author_facet Ziyad AlHammad
Ihab Suliman
Sami Alotaibi
Hourya Alnofaie
Waad Alsaadi
Sarah Alhusseini
Ghadah Aldakheel
Noura Alsubaie
author_sort Ziyad AlHammad
collection DOAJ
description Background: Orofacial clefts are considered one of the most common birth defects and are frequently associated with other malformations. Congenital heart disease is one of the most prevalent congenital malformation. Objective: To investigate the prevalence of congenital heart diseases associated with non-syndromic orofacial clefts in the Saudi population. Methods: Electronic files of non-syndromic orofacial cleft patients who visited the Oral and Maxillofacial Surgery Department in King Abdulaziz Medical City of Riyadh, Saudi Arabia from January 2015 to December 2018 were retrospectively reviewed. Data were recorded in an excel sheet and analyzed using SPSS via frequency tests. Results: In the cleft children identified, the prevalence of non-syndromic orofacial clefts was (77%). Orofacial clefts showed a male predominance (62%). The most common orofacial phenotype was unilateral cleft lip and palate (34%). The prevalence of associated congenital malformations with orofacial clefts was (41%). The most prevalent congenital malformation was congenital heart disease (35%), mainly found in unilateral cleft lip and palate patients (33%). The prevalence of associated congenital heart disease with orofacial clefts was (19%). The most frequent type of congenital heart disease was atrial septal defect (37%). Conclusion: This study highlights the recognition of the associated congenital heart disease with non-syndromic orofacial cleft patients. Global screening protocols designed for newborns with non-syndromic orofacial cleft are needed to eliminate late diagnosis of critical congenital heart diseases which might present operative risks of anesthesia and/or surgical procedures.
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series Saudi Dental Journal
spelling doaj-art-1403c80cc4cd45189063e7bfdafb49c32025-08-20T03:49:07ZengSpringerSaudi Dental Journal1013-90522021-03-0133313714210.1016/j.sdentj.2019.12.002The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi ArabiaZiyad AlHammad0Ihab Suliman1Sami Alotaibi2Hourya Alnofaie3Waad Alsaadi4Sarah Alhusseini5Ghadah Aldakheel6Noura Alsubaie7Saudi Board of Oral and Maxillofacial Surgery, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia; Corresponding author.Department of Cardiac Sciences, King Abdulaziz Medical City, Riyadh, Saudi ArabiaSaudi Board of Oral and Maxillofacial Surgery, Saudi Commission for Health Specialties, Riyadh, Saudi ArabiaSaudi Board of Oral and Maxillofacial Surgery, Saudi Commission for Health Specialties, Riyadh, Saudi Arabia; Division of Oral and Maxillofacial Surgery, Department of Basic Dental Sciences, College of Dentistry, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaPediatric Dentistry and Orthodontic Department, King Saud University, Riyadh, Saudi ArabiaCollege of Dentistry, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi ArabiaCollege of Dentistry, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi ArabiaCollege of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi ArabiaBackground: Orofacial clefts are considered one of the most common birth defects and are frequently associated with other malformations. Congenital heart disease is one of the most prevalent congenital malformation. Objective: To investigate the prevalence of congenital heart diseases associated with non-syndromic orofacial clefts in the Saudi population. Methods: Electronic files of non-syndromic orofacial cleft patients who visited the Oral and Maxillofacial Surgery Department in King Abdulaziz Medical City of Riyadh, Saudi Arabia from January 2015 to December 2018 were retrospectively reviewed. Data were recorded in an excel sheet and analyzed using SPSS via frequency tests. Results: In the cleft children identified, the prevalence of non-syndromic orofacial clefts was (77%). Orofacial clefts showed a male predominance (62%). The most common orofacial phenotype was unilateral cleft lip and palate (34%). The prevalence of associated congenital malformations with orofacial clefts was (41%). The most prevalent congenital malformation was congenital heart disease (35%), mainly found in unilateral cleft lip and palate patients (33%). The prevalence of associated congenital heart disease with orofacial clefts was (19%). The most frequent type of congenital heart disease was atrial septal defect (37%). Conclusion: This study highlights the recognition of the associated congenital heart disease with non-syndromic orofacial cleft patients. Global screening protocols designed for newborns with non-syndromic orofacial cleft are needed to eliminate late diagnosis of critical congenital heart diseases which might present operative risks of anesthesia and/or surgical procedures.http://www.sciencedirect.com/science/article/pii/S1013905219308387PrevalenceNon-syndromicOrofacial cleftCleft lip and palateCongenital heart diseaseSaudi Arabia
spellingShingle Ziyad AlHammad
Ihab Suliman
Sami Alotaibi
Hourya Alnofaie
Waad Alsaadi
Sarah Alhusseini
Ghadah Aldakheel
Noura Alsubaie
The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia
Saudi Dental Journal
Prevalence
Non-syndromic
Orofacial cleft
Cleft lip and palate
Congenital heart disease
Saudi Arabia
title The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia
title_full The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia
title_fullStr The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia
title_full_unstemmed The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia
title_short The prevalence of non-syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in Riyadh, Saudi Arabia
title_sort prevalence of non syndromic orofacial clefts and associated congenital heart diseases of a tertiary hospital in riyadh saudi arabia
topic Prevalence
Non-syndromic
Orofacial cleft
Cleft lip and palate
Congenital heart disease
Saudi Arabia
url http://www.sciencedirect.com/science/article/pii/S1013905219308387
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