Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit
Atypical hemolytic uremic syndrome (aHUS) is an orphan disease, representing one of thrombotic microangiopathies, the natural course of which leads to an unfavorable outcome often accompanied by multiple organ failure in the onset of the disease. Anesthesiologists and emergency physicians play an im...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2019-09-01
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| Series: | Вестник анестезиологии и реаниматологии |
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| Online Access: | https://www.vair-journal.com/jour/article/view/358 |
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| author | N. L. Kozlovskаya G. M. Gаlstyan V. N. Stepаnyuk |
| author_facet | N. L. Kozlovskаya G. M. Gаlstyan V. N. Stepаnyuk |
| author_sort | N. L. Kozlovskаya |
| collection | DOAJ |
| description | Atypical hemolytic uremic syndrome (aHUS) is an orphan disease, representing one of thrombotic microangiopathies, the natural course of which leads to an unfavorable outcome often accompanied by multiple organ failure in the onset of the disease. Anesthesiologists and emergency physicians play an important role in the multi-disciplinary team of specialists managing such patients. However, this disease is rare and its symptoms are similar to the ones of some other disorders including sepsis and disseminated intravascular coagulation syndrome, thus often aHUS is diagnosed late and specific treatment is not started in time. This article aims to present main notions related to thrombotic microangiopathies and discuss topical issues of differential diagnostics of aHUS in the intensive care units giving two clinical cases as an example. |
| format | Article |
| id | doaj-art-1403383e5c7f4131a013b4c8a1c0debb |
| institution | DOAJ |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2019-09-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-1403383e5c7f4131a013b4c8a1c0debb2025-08-20T02:59:45ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532019-09-01164657610.21292/2078-5658-2019-16-4-65-76335Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unitN. L. Kozlovskаya0G. M. Gаlstyan1V. N. Stepаnyuk2City Clinical Hospital named after A.K. Eramishantsev; Peoples’ Friendship University of RussiaNational Medical Research Center of HematologyPrimorskaya Regional Clinical Hospital no. 1Atypical hemolytic uremic syndrome (aHUS) is an orphan disease, representing one of thrombotic microangiopathies, the natural course of which leads to an unfavorable outcome often accompanied by multiple organ failure in the onset of the disease. Anesthesiologists and emergency physicians play an important role in the multi-disciplinary team of specialists managing such patients. However, this disease is rare and its symptoms are similar to the ones of some other disorders including sepsis and disseminated intravascular coagulation syndrome, thus often aHUS is diagnosed late and specific treatment is not started in time. This article aims to present main notions related to thrombotic microangiopathies and discuss topical issues of differential diagnostics of aHUS in the intensive care units giving two clinical cases as an example.https://www.vair-journal.com/jour/article/view/358thrombotic microangiopathyatypical hemolytic uremic syndromesepsisdisseminated intravascular coagulation syndrome |
| spellingShingle | N. L. Kozlovskаya G. M. Gаlstyan V. N. Stepаnyuk Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit Вестник анестезиологии и реаниматологии thrombotic microangiopathy atypical hemolytic uremic syndrome sepsis disseminated intravascular coagulation syndrome |
| title | Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit |
| title_full | Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit |
| title_fullStr | Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit |
| title_full_unstemmed | Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit |
| title_short | Difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit |
| title_sort | difficulties in diagnostics of atypical hemolytic uremic syndrome in the intensive care unit |
| topic | thrombotic microangiopathy atypical hemolytic uremic syndrome sepsis disseminated intravascular coagulation syndrome |
| url | https://www.vair-journal.com/jour/article/view/358 |
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