High-throughput, single-copy sequencing reveals SARS-CoV-2 spike variants coincident with mounting humoral immunity during acute COVID-19.

High-throughput, single-copy sequencing reveals SARS-CoV-2 spike variants coincident with mounting humoral immunity during acute COVID-19.

Tracking evolution of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within infected individuals will help elucidate coronavirus disease 2019 (COVID-19) pathogenesis and inform use of antiviral interventions. In this study, we developed an approach for sequencing the region encodin...

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Main Authors: Sung Hee Ko, Elham Bayat Mokhtari, Prakriti Mudvari, Sydney Stein, Christopher D Stringham, Danielle Wagner, Sabrina Ramelli, Marcos J Ramos-Benitez, Jeffrey R Strich, Richard T Davey, Tongqing Zhou, John Misasi, Peter D Kwong, Daniel S Chertow, Nancy J Sullivan, Eli A Boritz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-04-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009431&type=printable
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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1009431&type=printable

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