Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application

This article focused on development of an innovative glucose sensing platform utilizing Cr2O3 nanoparticles, presenting promising sensing parameters for non-enzymatic glucose detection. The synthesis of Cr2O3 nanoparticles is executed by a facile hydrothermal approach and their glucose sensing perfo...

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Main Authors: Rashmita Panda, Shakti Prasad Mishra, Bhagaban Kisan, Kusha K. Naik
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Next Materials
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949822825001662
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author Rashmita Panda
Shakti Prasad Mishra
Bhagaban Kisan
Kusha K. Naik
author_facet Rashmita Panda
Shakti Prasad Mishra
Bhagaban Kisan
Kusha K. Naik
author_sort Rashmita Panda
collection DOAJ
description This article focused on development of an innovative glucose sensing platform utilizing Cr2O3 nanoparticles, presenting promising sensing parameters for non-enzymatic glucose detection. The synthesis of Cr2O3 nanoparticles is executed by a facile hydrothermal approach and their glucose sensing performance is investigated intensively. The Cr2O3 nanoparticles are characterized by spectroscopic tools such as X-ray diffraction (XRD), UV-Vis spectroscopy, field effect scanning electron microscopy (FESEM) and tunneling electron microscopy (TEM) for morphological and crystallographic analysis. The Cr2O3 nanoparticles possess a high active surface area, which holds many electrocatalytic and biocatalytic centers to promote electronic/ionic transport in the electrode, leading to the improvement of glucose sensing performance. Electrochemical sensing parameters of the synthesized nanoparticles are evaluated using 0.1 M NaOH as an electrolytic solution. The sensitivity of Cr2O3 nanoparticles for electrochemical glucose sensing is calculated to be 9.35 × 10−4 μA μM−1cm−2 in the linear range of 330–1560 μM and 4.69 × 10−4 μA μM−1cm−2 in the linear range of 1560–3610 μM having response time of 9 s and detection limit of 80 μM. The prepared nanoparticles also exhibit excellent selectivity, stability and reproducibility towards glucose biomolecules.
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spelling doaj-art-13fc5d3a96fa4bb183fe59401c4ed9c22025-08-20T03:18:12ZengElsevierNext Materials2949-82282025-07-01810064810.1016/j.nxmate.2025.100648Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing applicationRashmita Panda0Shakti Prasad Mishra1Bhagaban Kisan2Kusha K. Naik3P.G Dept. of Physics, Berhampur University, Bhanja Bihar, Odisha 760007, IndiaP.G Dept. of Physics, Berhampur University, Bhanja Bihar, Odisha 760007, IndiaSchool of Physical Science, Jawaharlal Nehru University, New Delhi, IndiaP.G Dept. of Physics, Berhampur University, Bhanja Bihar, Odisha 760007, India; Corresponding author.This article focused on development of an innovative glucose sensing platform utilizing Cr2O3 nanoparticles, presenting promising sensing parameters for non-enzymatic glucose detection. The synthesis of Cr2O3 nanoparticles is executed by a facile hydrothermal approach and their glucose sensing performance is investigated intensively. The Cr2O3 nanoparticles are characterized by spectroscopic tools such as X-ray diffraction (XRD), UV-Vis spectroscopy, field effect scanning electron microscopy (FESEM) and tunneling electron microscopy (TEM) for morphological and crystallographic analysis. The Cr2O3 nanoparticles possess a high active surface area, which holds many electrocatalytic and biocatalytic centers to promote electronic/ionic transport in the electrode, leading to the improvement of glucose sensing performance. Electrochemical sensing parameters of the synthesized nanoparticles are evaluated using 0.1 M NaOH as an electrolytic solution. The sensitivity of Cr2O3 nanoparticles for electrochemical glucose sensing is calculated to be 9.35 × 10−4 μA μM−1cm−2 in the linear range of 330–1560 μM and 4.69 × 10−4 μA μM−1cm−2 in the linear range of 1560–3610 μM having response time of 9 s and detection limit of 80 μM. The prepared nanoparticles also exhibit excellent selectivity, stability and reproducibility towards glucose biomolecules.http://www.sciencedirect.com/science/article/pii/S2949822825001662Glucose sensorSensitivityElectrochemical methodHydrothermal methodNanoparticles
spellingShingle Rashmita Panda
Shakti Prasad Mishra
Bhagaban Kisan
Kusha K. Naik
Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application
Next Materials
Glucose sensor
Sensitivity
Electrochemical method
Hydrothermal method
Nanoparticles
title Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application
title_full Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application
title_fullStr Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application
title_full_unstemmed Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application
title_short Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application
title_sort investigation on electrochemical properties of chromium oxide nanoparticles for non enzymatic glucose sensing application
topic Glucose sensor
Sensitivity
Electrochemical method
Hydrothermal method
Nanoparticles
url http://www.sciencedirect.com/science/article/pii/S2949822825001662
work_keys_str_mv AT rashmitapanda investigationonelectrochemicalpropertiesofchromiumoxidenanoparticlesfornonenzymaticglucosesensingapplication
AT shaktiprasadmishra investigationonelectrochemicalpropertiesofchromiumoxidenanoparticlesfornonenzymaticglucosesensingapplication
AT bhagabankisan investigationonelectrochemicalpropertiesofchromiumoxidenanoparticlesfornonenzymaticglucosesensingapplication
AT kushaknaik investigationonelectrochemicalpropertiesofchromiumoxidenanoparticlesfornonenzymaticglucosesensingapplication