Investigation on electrochemical properties of chromium oxide nanoparticles for non-enzymatic glucose sensing application

This article focused on development of an innovative glucose sensing platform utilizing Cr2O3 nanoparticles, presenting promising sensing parameters for non-enzymatic glucose detection. The synthesis of Cr2O3 nanoparticles is executed by a facile hydrothermal approach and their glucose sensing perfo...

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Bibliographic Details
Main Authors: Rashmita Panda, Shakti Prasad Mishra, Bhagaban Kisan, Kusha K. Naik
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Next Materials
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Online Access:http://www.sciencedirect.com/science/article/pii/S2949822825001662
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Summary:This article focused on development of an innovative glucose sensing platform utilizing Cr2O3 nanoparticles, presenting promising sensing parameters for non-enzymatic glucose detection. The synthesis of Cr2O3 nanoparticles is executed by a facile hydrothermal approach and their glucose sensing performance is investigated intensively. The Cr2O3 nanoparticles are characterized by spectroscopic tools such as X-ray diffraction (XRD), UV-Vis spectroscopy, field effect scanning electron microscopy (FESEM) and tunneling electron microscopy (TEM) for morphological and crystallographic analysis. The Cr2O3 nanoparticles possess a high active surface area, which holds many electrocatalytic and biocatalytic centers to promote electronic/ionic transport in the electrode, leading to the improvement of glucose sensing performance. Electrochemical sensing parameters of the synthesized nanoparticles are evaluated using 0.1 M NaOH as an electrolytic solution. The sensitivity of Cr2O3 nanoparticles for electrochemical glucose sensing is calculated to be 9.35 × 10−4 μA μM−1cm−2 in the linear range of 330–1560 μM and 4.69 × 10−4 μA μM−1cm−2 in the linear range of 1560–3610 μM having response time of 9 s and detection limit of 80 μM. The prepared nanoparticles also exhibit excellent selectivity, stability and reproducibility towards glucose biomolecules.
ISSN:2949-8228