Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions

The theory of connection between respiratory and gastrointestinal systems is a key topic in different types of traditional medicine. In this study, we discussed the history, main concepts of this theory along with related studies and its possible clinical applications. In this regard numerous scatt...

Full description

Saved in:
Bibliographic Details
Main Authors: Shahin Saeidinejat, Syed Mohd Abbas Zaidi, Alireza Ranjbar, Alireza Derakhshan
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-12-01
Series:Traditional and Integrative Medicine
Subjects:
Online Access:https://jtim.tums.ac.ir/index.php/jtim/article/view/1254
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1823863739721449472
author Shahin Saeidinejat
Syed Mohd Abbas Zaidi
Alireza Ranjbar
Alireza Derakhshan
author_facet Shahin Saeidinejat
Syed Mohd Abbas Zaidi
Alireza Ranjbar
Alireza Derakhshan
author_sort Shahin Saeidinejat
collection DOAJ
description The theory of connection between respiratory and gastrointestinal systems is a key topic in different types of traditional medicine. In this study, we discussed the history, main concepts of this theory along with related studies and its possible clinical applications. In this regard numerous scattered studies have shown a relationship between upper and lower respiratory disorders and gastrointestinal symptoms.  Numerous epidemiologic, pathophysiologic and clinical evidence confirm the interrelationship and integrated functioning of the respiratory and gastrointestinal tracts. It seems that the holistic approach that emphasizes the link between the respiratory and gastrointestinal systems in traditional Persian medicine, is in line with the theory of united mucosa that has been considered in recent years. The interaction between the respiratory and gastrointestinal systems can occur through several mechanisms, including commonalities in embryonic sources, role of identical mediators and receptors, influence of common pathogens in the lungs and gut, similarity of microbiota patterns and changes, and same inflammatory and mucosal responses. We believe that this theory can provide new insight for the approaches to respiratory and gastrointestinal disorders in the light of holistic medical knowledge. Also, further research should be conducted to identify the exact paths and mechanisms of communication between respiratory and gastrointestinal systems.
format Article
id doaj-art-13fa52b124ee479db94aeee5ad655136
institution Kabale University
issn 2476-5104
2476-5112
language English
publishDate 2024-12-01
publisher Tehran University of Medical Sciences
record_format Article
series Traditional and Integrative Medicine
spelling doaj-art-13fa52b124ee479db94aeee5ad6551362025-02-09T09:11:26ZengTehran University of Medical SciencesTraditional and Integrative Medicine2476-51042476-51122024-12-019410.18502/tim.v9i4.17481Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future DirectionsShahin Saeidinejat0Syed Mohd Abbas Zaidi1Alireza Ranjbar2Alireza Derakhshan3School of Persian and Complementary Medicine, Mashhad University of Medical Sciences. Mashhad, IranDepartment of Moalejat, H.S.Z.H. Govt. Unani Medical College, Bhopal (M.P), IndiaInstitute of Interventional Allergology und Immunology, Bonn, Cologne, GermanySchool of Persian and Complementary Medicine, Mashhad University of Medical Sciences. Mashhad, Iran The theory of connection between respiratory and gastrointestinal systems is a key topic in different types of traditional medicine. In this study, we discussed the history, main concepts of this theory along with related studies and its possible clinical applications. In this regard numerous scattered studies have shown a relationship between upper and lower respiratory disorders and gastrointestinal symptoms.  Numerous epidemiologic, pathophysiologic and clinical evidence confirm the interrelationship and integrated functioning of the respiratory and gastrointestinal tracts. It seems that the holistic approach that emphasizes the link between the respiratory and gastrointestinal systems in traditional Persian medicine, is in line with the theory of united mucosa that has been considered in recent years. The interaction between the respiratory and gastrointestinal systems can occur through several mechanisms, including commonalities in embryonic sources, role of identical mediators and receptors, influence of common pathogens in the lungs and gut, similarity of microbiota patterns and changes, and same inflammatory and mucosal responses. We believe that this theory can provide new insight for the approaches to respiratory and gastrointestinal disorders in the light of holistic medical knowledge. Also, further research should be conducted to identify the exact paths and mechanisms of communication between respiratory and gastrointestinal systems. https://jtim.tums.ac.ir/index.php/jtim/article/view/1254Respiratory systemDigestive systemGut-Lung axisPersian medicineComplementary medicine
spellingShingle Shahin Saeidinejat
Syed Mohd Abbas Zaidi
Alireza Ranjbar
Alireza Derakhshan
Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions
Traditional and Integrative Medicine
Respiratory system
Digestive system
Gut-Lung axis
Persian medicine
Complementary medicine
title Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions
title_full Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions
title_fullStr Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions
title_full_unstemmed Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions
title_short Exploring the Ancient Persian/Unani Theory of Connection between Gastrointestinal and Respiratory Tracts: Current Evidence and Future Directions
title_sort exploring the ancient persian unani theory of connection between gastrointestinal and respiratory tracts current evidence and future directions
topic Respiratory system
Digestive system
Gut-Lung axis
Persian medicine
Complementary medicine
url https://jtim.tums.ac.ir/index.php/jtim/article/view/1254
work_keys_str_mv AT shahinsaeidinejat exploringtheancientpersianunanitheoryofconnectionbetweengastrointestinalandrespiratorytractscurrentevidenceandfuturedirections
AT syedmohdabbaszaidi exploringtheancientpersianunanitheoryofconnectionbetweengastrointestinalandrespiratorytractscurrentevidenceandfuturedirections
AT alirezaranjbar exploringtheancientpersianunanitheoryofconnectionbetweengastrointestinalandrespiratorytractscurrentevidenceandfuturedirections
AT alirezaderakhshan exploringtheancientpersianunanitheoryofconnectionbetweengastrointestinalandrespiratorytractscurrentevidenceandfuturedirections