Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach

This study developed a novel dual-wavelength confocal laser speckle imaging platform. The system includes both visible and near-infrared lasers and two imaging modes: confocal and wide-field laser speckle contrast imaging. The experimental results confirm that the proposed system can be used to meas...

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Main Authors: E Du, Haohan Zheng, Honghui He, Shiguo Li, Cong Qiu, Weifeng Zhang, Guoqing Wang, Xingquan Li, Lan Ma, Shuhao Shen, Yuan Zhou
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Photonics
Subjects:
Online Access:https://www.mdpi.com/2304-6732/11/11/1085
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author E Du
Haohan Zheng
Honghui He
Shiguo Li
Cong Qiu
Weifeng Zhang
Guoqing Wang
Xingquan Li
Lan Ma
Shuhao Shen
Yuan Zhou
author_facet E Du
Haohan Zheng
Honghui He
Shiguo Li
Cong Qiu
Weifeng Zhang
Guoqing Wang
Xingquan Li
Lan Ma
Shuhao Shen
Yuan Zhou
author_sort E Du
collection DOAJ
description This study developed a novel dual-wavelength confocal laser speckle imaging platform. The system includes both visible and near-infrared lasers and two imaging modes: confocal and wide-field laser speckle contrast imaging. The experimental results confirm that the proposed system can be used to measure not only blood flow but also blood oxygen saturation. Additionally, we proposed a blood flow perfusion imaging method called BlingNet (a blood flow imaging CNN) based on the laser speckle contrast imaging technique and deep learning approach. Compared to the traditional nonlinear fitting method, this method has superior accuracy and robustness with higher imaging speed, making real-time blood flow imaging possible.
format Article
id doaj-art-13f58d5433bc40a195ed8bc4039d396d
institution OA Journals
issn 2304-6732
language English
publishDate 2024-11-01
publisher MDPI AG
record_format Article
series Photonics
spelling doaj-art-13f58d5433bc40a195ed8bc4039d396d2025-08-20T01:54:03ZengMDPI AGPhotonics2304-67322024-11-011111108510.3390/photonics11111085Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning ApproachE Du0Haohan Zheng1Honghui He2Shiguo Li3Cong Qiu4Weifeng Zhang5Guoqing Wang6Xingquan Li7Lan Ma8Shuhao Shen9Yuan Zhou10School of Microelectronics, Shenzhen Institute of Information Technology, Shenzhen 518172, ChinaTsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaTsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaSchool of Microelectronics, Shenzhen Institute of Information Technology, Shenzhen 518172, ChinaSchool of Microelectronics, Shenzhen Institute of Information Technology, Shenzhen 518172, ChinaSchool of Microelectronics, Shenzhen Institute of Information Technology, Shenzhen 518172, ChinaSchool of Microelectronics, Shenzhen Institute of Information Technology, Shenzhen 518172, ChinaSchool of Microelectronics, Shenzhen Institute of Information Technology, Shenzhen 518172, ChinaGuangzhou Institute of Technology, Xidian University, Guangzhou 510555, ChinaGuangzhou Institute of Technology, Xidian University, Guangzhou 510555, ChinaShenzhen Stomatological Hospital, Southern Medical University, Shenzhen 518005, ChinaThis study developed a novel dual-wavelength confocal laser speckle imaging platform. The system includes both visible and near-infrared lasers and two imaging modes: confocal and wide-field laser speckle contrast imaging. The experimental results confirm that the proposed system can be used to measure not only blood flow but also blood oxygen saturation. Additionally, we proposed a blood flow perfusion imaging method called BlingNet (a blood flow imaging CNN) based on the laser speckle contrast imaging technique and deep learning approach. Compared to the traditional nonlinear fitting method, this method has superior accuracy and robustness with higher imaging speed, making real-time blood flow imaging possible.https://www.mdpi.com/2304-6732/11/11/1085laser speckleblood flowhemoglobin oxygen saturationconfocaldeep learning
spellingShingle E Du
Haohan Zheng
Honghui He
Shiguo Li
Cong Qiu
Weifeng Zhang
Guoqing Wang
Xingquan Li
Lan Ma
Shuhao Shen
Yuan Zhou
Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach
Photonics
laser speckle
blood flow
hemoglobin oxygen saturation
confocal
deep learning
title Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach
title_full Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach
title_fullStr Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach
title_full_unstemmed Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach
title_short Dual-Wavelength Confocal Laser Speckle Contrast Imaging Using a Deep Learning Approach
title_sort dual wavelength confocal laser speckle contrast imaging using a deep learning approach
topic laser speckle
blood flow
hemoglobin oxygen saturation
confocal
deep learning
url https://www.mdpi.com/2304-6732/11/11/1085
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