Retention of locally injected human iPS cell-derived cardiomyocytes into the myocardium using hydrolyzed gelatin

Retention of locally injected human iPS cell-derived cardiomyocytes into the myocardium using hydrolyzed gelatin

Abstract This study explored the impact of hydrolyzed gelatin (HG) concentration on the retention and therapeutic efficacy of human iPS cell-derived cardiomyocytes (hiPSC-CMs) when injected into the myocardium. The solubility of HG allows precise control over its concentration, influencing the distr...

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Bibliographic Details
Main Authors: Jun Iida, Kazuki Kotani, Kozue Murata, Keisuke Hakamada, Wusiman Maihemuti, Yoshinobu Mandai, Yosuke Hiraoka, Kenji Minatoya, Hidetoshi Masumoto
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-87885-w
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