A novel circular RNA circ_0020647 promotes ETEC-induced IPEC-J2 cell pyroptosis via the ssc-miR-185/BRD4 axis

A novel circular RNA circ_0020647 promotes ETEC-induced IPEC-J2 cell pyroptosis via the ssc-miR-185/BRD4 axis

IntroductionEnterotoxigenic E. coli (ETEC) is a major pathogen causing piglet diarrhea. This study aimed to investigate the mechanism of porcine circular RNAs (circRNAs) in regulating intestinal immunity during ETEC infection.MethodsThe circRNA expression profiles were obtained in ETEC-infected and...

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Bibliographic Details
Main Authors: Kaiqing Zhu, Puyu Liu, Kangping Liu, Yanan Cui, Pengxin Jiang, Xutao Wang, Ning Chen, Jiamei Cui, Zijuan Hou, Jianguo Li, Jinghui Fan, Yuzhu Zuo, Yan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Veterinary Science
Subjects:
circ_0020647
ssc-miR-185
BRD4
ETEC
IPEC-J2
pyroptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2025.1578941/full
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