The antineoplastic effects of nuciferine on hepatocellular carcinoma are associated with suppression of the HER2-AKT/ERK1/2 signaling pathway

The antineoplastic effects of nuciferine on hepatocellular carcinoma are associated with suppression of the HER2-AKT/ERK1/2 signaling pathway

Abstract Hepatocellular carcinoma (HCC) has the sixth highest morbidity and fourth highest mortality worldwide. Nuciferine (NF) is an aporphine alkaloid isolated from the leaves of Nelumbo nucifera Gaertn that showed good antineoplastic effects in various malignancies. However, the specific effects...

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Bibliographic Details
Main Authors: Tiantian Li, Weidong Wang, Mingwei Zhu, Tianxiu Dong, Jian Jiang, Zizhuo Li, Tingting An, Xi Chen, Yingxuan Mao, Yaodong Chen, Xiuhua Yang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Hepatocellular carcinoma
Nuciferine
Cell cycle
Proliferation
Apoptosis
Online Access:https://doi.org/10.1007/s12672-025-02695-w
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