Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation
Vaccination against human papillomavirus infection is not included in the National Calendar of Preventive Vaccinations of the Russian Federation, and vaccination is only available through regional programs. At the same time, the costeffectiveness of vaccination in the regions of the Russian Federat...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2024-12-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/1715 |
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| author | A. V. Rudakova S. M. Kharit Yu. V. Lobzin |
| author_facet | A. V. Rudakova S. M. Kharit Yu. V. Lobzin |
| author_sort | A. V. Rudakova |
| collection | DOAJ |
| description | Vaccination against human papillomavirus infection is not included in the National Calendar of Preventive Vaccinations of the Russian Federation, and vaccination is only available through regional programs. At the same time, the costeffectiveness of vaccination in the regions of the Russian Federation may vary significantly.The aim of this study was to assess the costeffectiveness of vaccination with the 4valent HPV vaccine in 12yearold girls in the regions of the Russian Federation.Materials and methods. A Markov model with a lifetime horizon for 12yearold girls based on epidemiological data for the Russian Federation was used. The costeffectiveness analysis was carried out from societal perspective. Costs and life expectancy were discounted at 3% per year.Results. In most regions of the Russian Federation, vaccination of girls is cost saving or highly costeffective (the cost per additional qualityadjusted life year (QALY) does not exceed the value of gross regional product per capita). Only in Dagestan, Chechnya and Ingushetia the vaccination of girls can be considered as costeffective, but not highly costeffective tool (incremental costs per QALY exceed the GRP per capita by 14,237,0%).Conclusions. Vaccination of girls before the onset of sexual activity with the 4valent HPV vaccine is highly costeffective in most regions of the Russian Federation. |
| format | Article |
| id | doaj-art-13e42ec6fd724939b5d1a46d7d4b7f89 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2024-12-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-13e42ec6fd724939b5d1a46d7d4b7f892025-08-20T03:38:30ZrusJournal InfectologyЖурнал инфектологии2072-67322024-12-011649910410.22625/2072-6732-2024-16-4-99-1041190Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian FederationA. V. Rudakova0S. M. Kharit1Yu. V. Lobzin2Pediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Chemical and Pharmaceutical UniversityPediatric Research and Clinical Center for Infectious Diseases; Saint-Petersburg State Pediatric Medical UniversityPediatric Research and Clinical Center for Infectious Diseases; North-Western State Medical University named after. I.I. MechnikovVaccination against human papillomavirus infection is not included in the National Calendar of Preventive Vaccinations of the Russian Federation, and vaccination is only available through regional programs. At the same time, the costeffectiveness of vaccination in the regions of the Russian Federation may vary significantly.The aim of this study was to assess the costeffectiveness of vaccination with the 4valent HPV vaccine in 12yearold girls in the regions of the Russian Federation.Materials and methods. A Markov model with a lifetime horizon for 12yearold girls based on epidemiological data for the Russian Federation was used. The costeffectiveness analysis was carried out from societal perspective. Costs and life expectancy were discounted at 3% per year.Results. In most regions of the Russian Federation, vaccination of girls is cost saving or highly costeffective (the cost per additional qualityadjusted life year (QALY) does not exceed the value of gross regional product per capita). Only in Dagestan, Chechnya and Ingushetia the vaccination of girls can be considered as costeffective, but not highly costeffective tool (incremental costs per QALY exceed the GRP per capita by 14,237,0%).Conclusions. Vaccination of girls before the onset of sexual activity with the 4valent HPV vaccine is highly costeffective in most regions of the Russian Federation.https://journal.niidi.ru/jofin/article/view/1715human papilloma virusvaccinationgirlsmarkov modelcosteffectivenessregional programs |
| spellingShingle | A. V. Rudakova S. M. Kharit Yu. V. Lobzin Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation Журнал инфектологии human papilloma virus vaccination girls markov model costeffectiveness regional programs |
| title | Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation |
| title_full | Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation |
| title_fullStr | Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation |
| title_full_unstemmed | Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation |
| title_short | Cost-effectiveness of vaccination against HPV of adolescent girls in the regions of Russian Federation |
| title_sort | cost effectiveness of vaccination against hpv of adolescent girls in the regions of russian federation |
| topic | human papilloma virus vaccination girls markov model costeffectiveness regional programs |
| url | https://journal.niidi.ru/jofin/article/view/1715 |
| work_keys_str_mv | AT avrudakova costeffectivenessofvaccinationagainsthpvofadolescentgirlsintheregionsofrussianfederation AT smkharit costeffectivenessofvaccinationagainsthpvofadolescentgirlsintheregionsofrussianfederation AT yuvlobzin costeffectivenessofvaccinationagainsthpvofadolescentgirlsintheregionsofrussianfederation |