Primary Breast Anaplastic Large-Cell Lymphoma
We reported a rare case and experience of successfully treating primary anaplastic large-cell lymphoma (ALCL) of the breast with no history of breast implants, using a combination of novel brentuximab vedotin and chemotherapy. A 78-year-old woman presented with a painless lump over the left breast....
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-10-01
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| Series: | Journal of Cancer Research and Practice |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00017 |
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| _version_ | 1832591011016081408 |
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| author | Min-Hong Wang Hui-Hua Hsiao |
| author_facet | Min-Hong Wang Hui-Hua Hsiao |
| author_sort | Min-Hong Wang |
| collection | DOAJ |
| description | We reported a rare case and experience of successfully treating primary anaplastic large-cell lymphoma (ALCL) of the breast with no history of breast implants, using a combination of novel brentuximab vedotin and chemotherapy. A 78-year-old woman presented with a painless lump over the left breast. The computed tomography scan revealed a 2.6-cm tumor in the left upper quadrant of the breast, along with enlarged lymph nodes in the left axilla, exhibiting similar imaging features to breast carcinoma. The definitive diagnosis was based on histopathology and immunohistochemistry stains consistent with ALCL. The patient received brentuximab vedotin in combination with cyclophosphamide, doxorubicin, and prednisone (CHP) chemotherapy, as well as involved site radiation therapy (ISRT). The following image showed almost complete remission. |
| format | Article |
| id | doaj-art-13e1bc986f6048038fd0bb631b801036 |
| institution | Kabale University |
| issn | 2311-3006 |
| language | English |
| publishDate | 2023-10-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Cancer Research and Practice |
| spelling | doaj-art-13e1bc986f6048038fd0bb631b8010362025-01-23T05:09:32ZengWolters Kluwer Medknow PublicationsJournal of Cancer Research and Practice2311-30062023-10-0110415816010.4103/ejcrp.eJCRP-D-23-00017Primary Breast Anaplastic Large-Cell LymphomaMin-Hong WangHui-Hua HsiaoWe reported a rare case and experience of successfully treating primary anaplastic large-cell lymphoma (ALCL) of the breast with no history of breast implants, using a combination of novel brentuximab vedotin and chemotherapy. A 78-year-old woman presented with a painless lump over the left breast. The computed tomography scan revealed a 2.6-cm tumor in the left upper quadrant of the breast, along with enlarged lymph nodes in the left axilla, exhibiting similar imaging features to breast carcinoma. The definitive diagnosis was based on histopathology and immunohistochemistry stains consistent with ALCL. The patient received brentuximab vedotin in combination with cyclophosphamide, doxorubicin, and prednisone (CHP) chemotherapy, as well as involved site radiation therapy (ISRT). The following image showed almost complete remission.https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00017anaplastic large-cell lymphomacase reportprimary breast lymphomat-cell lymphoma |
| spellingShingle | Min-Hong Wang Hui-Hua Hsiao Primary Breast Anaplastic Large-Cell Lymphoma Journal of Cancer Research and Practice anaplastic large-cell lymphoma case report primary breast lymphoma t-cell lymphoma |
| title | Primary Breast Anaplastic Large-Cell Lymphoma |
| title_full | Primary Breast Anaplastic Large-Cell Lymphoma |
| title_fullStr | Primary Breast Anaplastic Large-Cell Lymphoma |
| title_full_unstemmed | Primary Breast Anaplastic Large-Cell Lymphoma |
| title_short | Primary Breast Anaplastic Large-Cell Lymphoma |
| title_sort | primary breast anaplastic large cell lymphoma |
| topic | anaplastic large-cell lymphoma case report primary breast lymphoma t-cell lymphoma |
| url | https://journals.lww.com/10.4103/ejcrp.eJCRP-D-23-00017 |
| work_keys_str_mv | AT minhongwang primarybreastanaplasticlargecelllymphoma AT huihuahsiao primarybreastanaplasticlargecelllymphoma |