Comparison of Medical Versus Surgical Treatment for Newly Diagnosed Cases of Primary Open Angle Glaucoma
Purpose: To compare the efficacy of 0.5% timolol maleate eye drops with trabeculectomy in the treatment of recently diagnosed cases Primary open angle glaucoma (POAG). Material and Methods: Total 60 patients were included in the study and were randomly divided into two groups of 30 patients each. Gr...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2012-10-01
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| Series: | Delhi Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.7869/djo.2012.52 |
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| Summary: | Purpose:
To compare the efficacy of 0.5% timolol maleate eye drops with trabeculectomy in the treatment of recently diagnosed cases Primary open angle glaucoma (POAG).
Material and Methods:
Total 60 patients were included in the study and were randomly divided into two groups of 30 patients each. Group A was treated with topical timolol maleate ophthalmic solution (0.5%) twice daily while Group B was treated surgically by trabeculectomy. Baseline IOP (intraocular pressure), visual acuity, visual fields and C:D (cup disc ratio) ratio were noted before the initiation of therapy in both groups. The subsequent follow up were done weekly for first two weeks then at one month and subsequently three monthly upto one year.
Results:
In the present study, the mean reduction in IOP at the end of 1 year was 8.20 ± 0.75 mm Hg in group A and 10.40 ± 0.28 mm of Hg in group B. Greater IOP reduction was seen in group B. Although no significant change in CD ratio was observed in the two groups. In group A 30 % patients had deterioration in visual fields whereas in group B deterioration was seen in 15% patients. The visual acuity remained stable in both the study groups.
Conclusion:
In the present study it was concluded that mean IOP, visual field and visual acuity were better controlled on surgical treatment as compared to medical treatment. |
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| ISSN: | 0972-0200 2454-2784 |