Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study

Introduction Metabolic disturbances are of major health concerns in the world. In addition to their high prevalence, these disorders have substantial roles in developing other physical and mental diseases. Diet could have a considerable influence on managing the progression of these conditions and t...

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Main Authors: Donya Poursalehi, Farnaz Shahdadian, Zahra Hajhashemy, Keyhan Lotfi, Zahra Moradmand, Parisa Rouhani, Sobhan Mohammadi, Elahe Mokhtari, Parvane Saneei
Format: Article
Language:English
Published: BMJ Publishing Group 2023-12-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/13/12/e076114.full
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author Donya Poursalehi
Farnaz Shahdadian
Zahra Hajhashemy
Keyhan Lotfi
Zahra Moradmand
Parisa Rouhani
Sobhan Mohammadi
Elahe Mokhtari
Parvane Saneei
author_facet Donya Poursalehi
Farnaz Shahdadian
Zahra Hajhashemy
Keyhan Lotfi
Zahra Moradmand
Parisa Rouhani
Sobhan Mohammadi
Elahe Mokhtari
Parvane Saneei
author_sort Donya Poursalehi
collection DOAJ
description Introduction Metabolic disturbances are of major health concerns in the world. In addition to their high prevalence, these disorders have substantial roles in developing other physical and mental diseases. Diet could have a considerable influence on managing the progression of these conditions and their consequent health-related effects. The aim of the ‘Diet in relation to Metabolic, sleep and psychological health Status’ Project is to explore the association of nutrition with metabolic, sleep and mental health, considering potential mediators including brain-derived neurotrophic factor (BDNF) and adropin.Methods and analysis This cross-sectional study will be conducted on adults (20–65 years) working in schools of Isfahan, Iran. A multistage cluster random sampling method will be used to select participants. Anthropometric, body composition and biochemical values including fasting blood glucose, lipid profile, 25-hydroxy vitamin D, insulin, BDNF, adropin, malondialdehyde, superoxide dismutase, glutathione peroxidase, uric acid, creatinine and C reactive protein will be measured for each participant. National Cholesterol Education Program and Adult Treatment Panel III will be considered to define metabolic syndrome. Diet will be assessed through a validated Food Frequency Questionnaire. Furthermore, sleep status, mental health, quality of life, physical activity and demographic status of individuals will be assessed by validated questionnaires. The collected data will be analysed using appropriate statistical methods.Ethics and dissemination The study protocol was approved by the local Ethics Committee of Isfahan University of Medical Sciences. All participants will provide written informed consent. Dissemination will be through conference presentations and publications in peer-reviewed journals.
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spelling doaj-art-13d898976ee44868825f84d3aef12f662025-08-20T03:11:58ZengBMJ Publishing GroupBMJ Open2044-60552023-12-01131210.1136/bmjopen-2023-076114Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional studyDonya Poursalehi0Farnaz Shahdadian1Zahra Hajhashemy2Keyhan Lotfi3Zahra Moradmand4Parisa Rouhani5Sobhan Mohammadi6Elahe Mokhtari7Parvane Saneei8Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Department of Clinical Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Department of Community Nutrition, Tehran University of Medical Sciences, Tehran, Iran (the Islamic Republic of)Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Department of Community Nutrition, Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Isfahan University of Medical Sciences, Isfahan, Iran (the Islamic Republic of)Introduction Metabolic disturbances are of major health concerns in the world. In addition to their high prevalence, these disorders have substantial roles in developing other physical and mental diseases. Diet could have a considerable influence on managing the progression of these conditions and their consequent health-related effects. The aim of the ‘Diet in relation to Metabolic, sleep and psychological health Status’ Project is to explore the association of nutrition with metabolic, sleep and mental health, considering potential mediators including brain-derived neurotrophic factor (BDNF) and adropin.Methods and analysis This cross-sectional study will be conducted on adults (20–65 years) working in schools of Isfahan, Iran. A multistage cluster random sampling method will be used to select participants. Anthropometric, body composition and biochemical values including fasting blood glucose, lipid profile, 25-hydroxy vitamin D, insulin, BDNF, adropin, malondialdehyde, superoxide dismutase, glutathione peroxidase, uric acid, creatinine and C reactive protein will be measured for each participant. National Cholesterol Education Program and Adult Treatment Panel III will be considered to define metabolic syndrome. Diet will be assessed through a validated Food Frequency Questionnaire. Furthermore, sleep status, mental health, quality of life, physical activity and demographic status of individuals will be assessed by validated questionnaires. The collected data will be analysed using appropriate statistical methods.Ethics and dissemination The study protocol was approved by the local Ethics Committee of Isfahan University of Medical Sciences. All participants will provide written informed consent. Dissemination will be through conference presentations and publications in peer-reviewed journals.https://bmjopen.bmj.com/content/13/12/e076114.full
spellingShingle Donya Poursalehi
Farnaz Shahdadian
Zahra Hajhashemy
Keyhan Lotfi
Zahra Moradmand
Parisa Rouhani
Sobhan Mohammadi
Elahe Mokhtari
Parvane Saneei
Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study
BMJ Open
title Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study
title_full Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study
title_fullStr Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study
title_full_unstemmed Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study
title_short Diet in relation to Metabolic, sleep and psychological health Status (DiMetS): protocol for a cross-sectional study
title_sort diet in relation to metabolic sleep and psychological health status dimets protocol for a cross sectional study
url https://bmjopen.bmj.com/content/13/12/e076114.full
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