Case Report: Intradural gout tophi without systemic gout symptoms
BackgroundGout is a common disease; however, a gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date.Case presentationWe report the case of a 70-year-old female who presented with lower back pain, right radicular pain, and numbness in the perineal are...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-02-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1472886/full |
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| author | Peidong Qing Shiming Xie Chaoqun Feng Hongda Xu Shengxin Zhao Lei Zhang Haitao Deng Yehui Wang Youpeng Hu |
| author_facet | Peidong Qing Shiming Xie Chaoqun Feng Hongda Xu Shengxin Zhao Lei Zhang Haitao Deng Yehui Wang Youpeng Hu |
| author_sort | Peidong Qing |
| collection | DOAJ |
| description | BackgroundGout is a common disease; however, a gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date.Case presentationWe report the case of a 70-year-old female who presented with lower back pain, right radicular pain, and numbness in the perineal area. Magnetic resonance imaging and computed tomography scans revealed a calcified intradural lesion at the L3 level. The diagnosis of the lesion was not definitive because the patient had no history of gout or manifestations of systemic gout. Surgical removal of the intradural lesion followed by pathological examination confirmed gouty tophi. The postoperative recovery was good, and the patient experienced substantial relief from pain and numbness.ConclusionThis is the third documented case of gout tophi occurring within the spinal dura. In a literature review, it was found that none of these three patients with intradural gouty tophi had systemic gout manifestations or hyperuricemia, which is a crucial finding. As it is challenging to diagnose intradural gout, awareness among physicians must be increased to optimize the treatment of, and outcomes for, these patients. |
| format | Article |
| id | doaj-art-13d256de8ec6497d990200b0ec112f2c |
| institution | Kabale University |
| issn | 2296-875X |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj-art-13d256de8ec6497d990200b0ec112f2c2025-02-10T06:48:33ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-02-011210.3389/fsurg.2025.14728861472886Case Report: Intradural gout tophi without systemic gout symptomsPeidong Qing0Shiming Xie1Chaoqun Feng2Hongda Xu3Shengxin Zhao4Lei Zhang5Haitao Deng6Yehui Wang7Youpeng Hu8Mianyang Orthopedic Hospital, Mianyang, ChinaMianyang Orthopedic Hospital, Mianyang, ChinaHospital of Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaMianyang Orthopedic Hospital, Mianyang, ChinaMianyang Orthopedic Hospital, Mianyang, ChinaMianyang Orthopedic Hospital, Mianyang, ChinaMianyang Orthopedic Hospital, Mianyang, ChinaSichuan Province Orthopedic Hospital, Chengdu, ChinaMianyang Orthopedic Hospital, Mianyang, ChinaBackgroundGout is a common disease; however, a gout tophus occurring within the spinal dura is exceedingly rare, with only two cases reported to date.Case presentationWe report the case of a 70-year-old female who presented with lower back pain, right radicular pain, and numbness in the perineal area. Magnetic resonance imaging and computed tomography scans revealed a calcified intradural lesion at the L3 level. The diagnosis of the lesion was not definitive because the patient had no history of gout or manifestations of systemic gout. Surgical removal of the intradural lesion followed by pathological examination confirmed gouty tophi. The postoperative recovery was good, and the patient experienced substantial relief from pain and numbness.ConclusionThis is the third documented case of gout tophi occurring within the spinal dura. In a literature review, it was found that none of these three patients with intradural gouty tophi had systemic gout manifestations or hyperuricemia, which is a crucial finding. As it is challenging to diagnose intradural gout, awareness among physicians must be increased to optimize the treatment of, and outcomes for, these patients.https://www.frontiersin.org/articles/10.3389/fsurg.2025.1472886/fullgout tophispinal duraintradural gouthyperuricemialumbar scoliosisneurological damage |
| spellingShingle | Peidong Qing Shiming Xie Chaoqun Feng Hongda Xu Shengxin Zhao Lei Zhang Haitao Deng Yehui Wang Youpeng Hu Case Report: Intradural gout tophi without systemic gout symptoms Frontiers in Surgery gout tophi spinal dura intradural gout hyperuricemia lumbar scoliosis neurological damage |
| title | Case Report: Intradural gout tophi without systemic gout symptoms |
| title_full | Case Report: Intradural gout tophi without systemic gout symptoms |
| title_fullStr | Case Report: Intradural gout tophi without systemic gout symptoms |
| title_full_unstemmed | Case Report: Intradural gout tophi without systemic gout symptoms |
| title_short | Case Report: Intradural gout tophi without systemic gout symptoms |
| title_sort | case report intradural gout tophi without systemic gout symptoms |
| topic | gout tophi spinal dura intradural gout hyperuricemia lumbar scoliosis neurological damage |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2025.1472886/full |
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