Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae
ObjectivesThis study aimed to evaluate the effects on bone repair of different concentrations of mineral trioxide aggregate (MTA) added to AH Plus.Materials and MethodsBone tissue reactions were evaluated in 30 rats (Rattus norvegicus) after 7 and 30 days. In the AH + MTA10, AH + MTA20, and AH + MTA...
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Korean Academy of Conservative Dentistry
2021-11-01
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| Series: | Restorative Dentistry & Endodontics |
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| Online Access: | http://rde.ac/upload/pdf/rde-46-e48.pdf |
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| author | Jessica Emanuella Rocha Paz Priscila Oliveira Costa Albert Alexandre Costa Souza Ingrid Macedo de Oliveira Lucas Fernandes Falcão Carlos Alberto Monteiro Falcão Maria Ângela Area Leão Ferraz Lucielma Salmito Soares Pinto |
| author_facet | Jessica Emanuella Rocha Paz Priscila Oliveira Costa Albert Alexandre Costa Souza Ingrid Macedo de Oliveira Lucas Fernandes Falcão Carlos Alberto Monteiro Falcão Maria Ângela Area Leão Ferraz Lucielma Salmito Soares Pinto |
| author_sort | Jessica Emanuella Rocha Paz |
| collection | DOAJ |
| description | ObjectivesThis study aimed to evaluate the effects on bone repair of different concentrations of mineral trioxide aggregate (MTA) added to AH Plus.Materials and MethodsBone tissue reactions were evaluated in 30 rats (Rattus norvegicus) after 7 and 30 days. In the AH + MTA10, AH + MTA20, and AH + MTA30 groups, defects in the tibiae were filled with AH Plus with MTA in proportions of 10%, 20% and 30%, respectively; in the MTA-FILL group, MTA Fillapex was used; and in the control group, no sealer was used. The samples were histologically analyzed to assess bone union and maturation. The Kruskal-Wallis and Mann-Whitney tests were performed for multiple pairwise comparisons (p ≤ 0.05).ResultsAt the 7-day time point, AH + MTA10 was superior to MTA-FILL with respect to bone union, and AH + MTA20 was superior to MTA-FILL with respect to bone maturity (p < 0.05). At the 30-day time point, both the AH + MTA10 and AH + MTA20 experimental sealers were superior not only to MTA-FILL, but also to AH + MTA30 with respect to both parameters (p < 0.05). The results of the AH + MTA10 and AH + MTA20 groups were superior to those of the control group for both parameters and experimental time points (p < 0.05).ConclusionsThe results suggest the potential benefit of using a combination of these materials in situations requiring bone repair. |
| format | Article |
| id | doaj-art-13c6fc4f01d94ce7bfae8030075741b5 |
| institution | DOAJ |
| issn | 2234-7658 2234-7666 |
| language | English |
| publishDate | 2021-11-01 |
| publisher | Korean Academy of Conservative Dentistry |
| record_format | Article |
| series | Restorative Dentistry & Endodontics |
| spelling | doaj-art-13c6fc4f01d94ce7bfae8030075741b52025-08-20T03:14:57ZengKorean Academy of Conservative DentistryRestorative Dentistry & Endodontics2234-76582234-76662021-11-01464e4810.5395/rde.2021.46.e48987Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiaeJessica Emanuella Rocha Paz0Priscila Oliveira Costa1Albert Alexandre Costa Souza2Ingrid Macedo de Oliveira3Lucas Fernandes Falcão4Carlos Alberto Monteiro Falcão5Maria Ângela Area Leão Ferraz6Lucielma Salmito Soares Pinto7Department of Oral & Maxillofacial Surgery and Periodontology, São Paulo University, School of Dentistry, Ribeirão Preto, SP, BrazilDepartment of Endodontics, Dental School, Uninovafapi University Center, Teresina, PI, BrazilDepartment of Endodontics, Dental School, Uninovafapi University Center, Teresina, PI, BrazilDepartment of Endodontics, Dental School, Uninovafapi University Center, Teresina, PI, BrazilDepartment of Endodontics, São Leopoldo Mandic Dental School, Campinas, SP, BrazilDepartment of Endodontics, Dental School, Uninovafapi University Center, Teresina, PI, BrazilDepartment of Endodontics, Dental School, Uninovafapi University Center, Teresina, PI, BrazilDepartment of Morphology, Health Science Center, State University of Piauí, Teresina, PI, BrazilObjectivesThis study aimed to evaluate the effects on bone repair of different concentrations of mineral trioxide aggregate (MTA) added to AH Plus.Materials and MethodsBone tissue reactions were evaluated in 30 rats (Rattus norvegicus) after 7 and 30 days. In the AH + MTA10, AH + MTA20, and AH + MTA30 groups, defects in the tibiae were filled with AH Plus with MTA in proportions of 10%, 20% and 30%, respectively; in the MTA-FILL group, MTA Fillapex was used; and in the control group, no sealer was used. The samples were histologically analyzed to assess bone union and maturation. The Kruskal-Wallis and Mann-Whitney tests were performed for multiple pairwise comparisons (p ≤ 0.05).ResultsAt the 7-day time point, AH + MTA10 was superior to MTA-FILL with respect to bone union, and AH + MTA20 was superior to MTA-FILL with respect to bone maturity (p < 0.05). At the 30-day time point, both the AH + MTA10 and AH + MTA20 experimental sealers were superior not only to MTA-FILL, but also to AH + MTA30 with respect to both parameters (p < 0.05). The results of the AH + MTA10 and AH + MTA20 groups were superior to those of the control group for both parameters and experimental time points (p < 0.05).ConclusionsThe results suggest the potential benefit of using a combination of these materials in situations requiring bone repair.http://rde.ac/upload/pdf/rde-46-e48.pdfah plusbone regenerationmineral trioxide aggregatemta fillapexrattus norvegicusroot canal sealers |
| spellingShingle | Jessica Emanuella Rocha Paz Priscila Oliveira Costa Albert Alexandre Costa Souza Ingrid Macedo de Oliveira Lucas Fernandes Falcão Carlos Alberto Monteiro Falcão Maria Ângela Area Leão Ferraz Lucielma Salmito Soares Pinto Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae Restorative Dentistry & Endodontics ah plus bone regeneration mineral trioxide aggregate mta fillapex rattus norvegicus root canal sealers |
| title | Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae |
| title_full | Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae |
| title_fullStr | Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae |
| title_full_unstemmed | Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae |
| title_short | Bone repair in defects filled with AH Plus sealer and different concentrations of MTA: a study in rat tibiae |
| title_sort | bone repair in defects filled with ah plus sealer and different concentrations of mta a study in rat tibiae |
| topic | ah plus bone regeneration mineral trioxide aggregate mta fillapex rattus norvegicus root canal sealers |
| url | http://rde.ac/upload/pdf/rde-46-e48.pdf |
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