ALKBH5 suppresses miR-29a-3p expression, thereby exacerbating the inflammatory response associated with spinal tuberculosis

ALKBH5 suppresses miR-29a-3p expression, thereby exacerbating the inflammatory response associated with spinal tuberculosis

Abstract Background N6-methyladenosine (m6A) is the most common and abundant internal modification in RNA. However, the role of m6A in spinal tuberculosis (STB) remains incompletely elucidated. In our previous study, miRNA-seq was performed on peripheral blood and tissues from STB patients, and miR-...

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Bibliographic Details
Main Authors: Mengqi Zhu, Zhengyong Tao, XingYu Duan, Lijun Feng, Xiaojun Ma, Jiong Wang, ZhiYun Shi, Xu Zhang, NingKui Niu
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Spinal tuberculosis
ALKBH5
miR-29a-3p
Inflammatory response
Online Access:https://doi.org/10.1186/s13018-025-06204-1
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