Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique

The rapid diagnosis of bovine tuberculosis (BT) allows official surveillance institutions to act in areas that could be potential hotspots for the spread of the disease. The study aimed to identify the Mycobacterium bovis agent by multiplex PCR of isolated colonies. Through the official inspection...

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Main Authors: Bruno Ribeiro dos Santos, Bianca Mendes Maciel, Alana Venâncio da Silva, Hllytchaikra Ferraz Fehlberg, Fernando Alzamora Filho
Format: Article
Language:English
Published: Universidade Federal de Goiás 2024-10-01
Series:Ciência Animal Brasileira
Online Access:https://revistas.ufg.br/vet/article/view/78409
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author Bruno Ribeiro dos Santos
Bianca Mendes Maciel
Alana Venâncio da Silva
Hllytchaikra Ferraz Fehlberg
Fernando Alzamora Filho
author_facet Bruno Ribeiro dos Santos
Bianca Mendes Maciel
Alana Venâncio da Silva
Hllytchaikra Ferraz Fehlberg
Fernando Alzamora Filho
author_sort Bruno Ribeiro dos Santos
collection DOAJ
description The rapid diagnosis of bovine tuberculosis (BT) allows official surveillance institutions to act in areas that could be potential hotspots for the spread of the disease. The study aimed to identify the Mycobacterium bovis agent by multiplex PCR of isolated colonies. Through the official inspection service (Federal/State), samples suggestive of BT were collected during the post-mortem inspection of bovine carcasses in slaughterhouses and sent to the laboratory for complementary diagnostics. The samples were analyzed using bacteriological culture and Ziehl-Neelsen staining. In isolates characterized as Acid-Alcohol Resistant Bacilli (BAAR), the multiplex PCR technique confirmed the agent Mycobacterium bovis. Nine hundred ninety-one thousand three hundred sixteen cattle carcasses were inspected, collecting 32 BT-suggestive samples in from animalsfrom 30 municipalities. Of these, 28.1% (9/32) showed growth on bacteriological culture media with BAAR. The BAAR isolates submitted to multiplex PCR confirmed the presence of M. bovis. The multiplex PCR technique associated with bacteriological examination and applied to post-mortem findings enabled the diagnosis of M. bovis in the municipalities sampled in the Bahia state.
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institution OA Journals
issn 1518-2797
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language English
publishDate 2024-10-01
publisher Universidade Federal de Goiás
record_format Article
series Ciência Animal Brasileira
spelling doaj-art-13bda39ea29045599f9544ed448b2b282025-08-20T02:17:01ZengUniversidade Federal de GoiásCiência Animal Brasileira1518-27971809-68912024-10-0125Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR techniqueBruno Ribeiro dos Santos 0Bianca Mendes Maciel1Alana Venâncio da Silva2Hllytchaikra Ferraz Fehlberg3Fernando Alzamora Filho4Universidade Estadual de Santa Cruz (UESC), Ilheus, Bahia, BrasilUniversidade Estadual de Santa Cruz (UESC), Ilheus, Bahia, BrasilUniversidade Estadual de Santa Cruz (UESC), Ilheus, Bahia, BrasilUniversidade Estadual de Santa Cruz (UESC), Ilheus, Bahia, BrasilUniversidade Estadual de Santa Cruz (UESC), Ilheus, Bahia, Brasil The rapid diagnosis of bovine tuberculosis (BT) allows official surveillance institutions to act in areas that could be potential hotspots for the spread of the disease. The study aimed to identify the Mycobacterium bovis agent by multiplex PCR of isolated colonies. Through the official inspection service (Federal/State), samples suggestive of BT were collected during the post-mortem inspection of bovine carcasses in slaughterhouses and sent to the laboratory for complementary diagnostics. The samples were analyzed using bacteriological culture and Ziehl-Neelsen staining. In isolates characterized as Acid-Alcohol Resistant Bacilli (BAAR), the multiplex PCR technique confirmed the agent Mycobacterium bovis. Nine hundred ninety-one thousand three hundred sixteen cattle carcasses were inspected, collecting 32 BT-suggestive samples in from animalsfrom 30 municipalities. Of these, 28.1% (9/32) showed growth on bacteriological culture media with BAAR. The BAAR isolates submitted to multiplex PCR confirmed the presence of M. bovis. The multiplex PCR technique associated with bacteriological examination and applied to post-mortem findings enabled the diagnosis of M. bovis in the municipalities sampled in the Bahia state. https://revistas.ufg.br/vet/article/view/78409
spellingShingle Bruno Ribeiro dos Santos
Bianca Mendes Maciel
Alana Venâncio da Silva
Hllytchaikra Ferraz Fehlberg
Fernando Alzamora Filho
Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique
Ciência Animal Brasileira
title Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique
title_full Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique
title_fullStr Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique
title_full_unstemmed Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique
title_short Bovine tuberculosis diagnosis in the state of Bahia, Brazil, using the multiplex PCR technique
title_sort bovine tuberculosis diagnosis in the state of bahia brazil using the multiplex pcr technique
url https://revistas.ufg.br/vet/article/view/78409
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