The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia
Patients with endometrial neoplasia (EN) often have multiple comorbidities and a higher surgical risk. Prehabilitation programs (PPs) combine various interventions to improve preoperative conditions and reduce impairment due to surgical stress. We conducted a pragmatic pilot study to evaluate the ac...
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MDPI AG
2025-01-01
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| Series: | Current Oncology |
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| Online Access: | https://www.mdpi.com/1718-7729/32/1/55 |
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| author | Elise P. Legault Paula A. B. Ribeiro Danielle Moreau-Amaru Emmanuelle Robert Sara Forte Alain S. Comtois Vanessa Samouëlian François Tournoux |
| author_facet | Elise P. Legault Paula A. B. Ribeiro Danielle Moreau-Amaru Emmanuelle Robert Sara Forte Alain S. Comtois Vanessa Samouëlian François Tournoux |
| author_sort | Elise P. Legault |
| collection | DOAJ |
| description | Patients with endometrial neoplasia (EN) often have multiple comorbidities and a higher surgical risk. Prehabilitation programs (PPs) combine various interventions to improve preoperative conditions and reduce impairment due to surgical stress. We conducted a pragmatic pilot study to evaluate the acceptability and feasibility of a trimodal telehealth PP (exercise, nutrition, and psychological support) for EN patients. The participants could select their exercise group: (1) a supervised PP (SPP), group sessions 3×/week; (2) a semi-supervised PP (SSPP), group session 1×/week, training alone 2×/week; or (3) a physical activity counseling session (PACS). Out of the 150 EN patients awaiting surgery screened during the 18 months of the study recruitment, 66% (99/150) were eligible, and 40% consented to participate (SPP, n = 13; SSPP, n = 17; PACS, n = 9). The overall dropout was low (13%; 5/39), with no significant differences across groups. No serious adverse events occurred. We observed a positive impact on different outcomes across the different groups, such as in the Functional Assessment of Cancer Therapy quality of life score (SPP; delta = 6.1 [CI: 0.9; 12.6]) and functional capacity measured using the 30″ sit-to-stand test (PACS delta = 2.4 [CI: 1.2; 3.6]). The same-day hospital leave was high in the SSPP group (54.5%). Our pilot telehealth PP seems to be safe, feasible, and well accepted and may procure clinical and patient-centered gains that need to be confirmed in a larger trial. |
| format | Article |
| id | doaj-art-13bc940d0f1a41a4a9f4f0343cbaa2d1 |
| institution | Kabale University |
| issn | 1198-0052 1718-7729 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Current Oncology |
| spelling | doaj-art-13bc940d0f1a41a4a9f4f0343cbaa2d12025-01-24T13:28:31ZengMDPI AGCurrent Oncology1198-00521718-77292025-01-013215510.3390/curroncol32010055The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial NeoplasiaElise P. Legault0Paula A. B. Ribeiro1Danielle Moreau-Amaru2Emmanuelle Robert3Sara Forte4Alain S. Comtois5Vanessa Samouëlian6François Tournoux7Coeurlab Research Unit, Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0A9, CanadaCoeurlab Research Unit, Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0A9, CanadaService de Gynécologie Oncologique du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0C1, CanadaService de Gynécologie Oncologique du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0C1, CanadaService de Gynécologie Oncologique du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0C1, CanadaDépartement des Sciences de l’Activité Physique, Université du Québec à Montréal, Montréal, QC H2L 1Y4, CanadaService de Gynécologie Oncologique du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0C1, CanadaCoeurlab Research Unit, Centre de Recherche du Centre Hospitalier de l’Université de Montréal, Montréal, QC H2X 0A9, CanadaPatients with endometrial neoplasia (EN) often have multiple comorbidities and a higher surgical risk. Prehabilitation programs (PPs) combine various interventions to improve preoperative conditions and reduce impairment due to surgical stress. We conducted a pragmatic pilot study to evaluate the acceptability and feasibility of a trimodal telehealth PP (exercise, nutrition, and psychological support) for EN patients. The participants could select their exercise group: (1) a supervised PP (SPP), group sessions 3×/week; (2) a semi-supervised PP (SSPP), group session 1×/week, training alone 2×/week; or (3) a physical activity counseling session (PACS). Out of the 150 EN patients awaiting surgery screened during the 18 months of the study recruitment, 66% (99/150) were eligible, and 40% consented to participate (SPP, n = 13; SSPP, n = 17; PACS, n = 9). The overall dropout was low (13%; 5/39), with no significant differences across groups. No serious adverse events occurred. We observed a positive impact on different outcomes across the different groups, such as in the Functional Assessment of Cancer Therapy quality of life score (SPP; delta = 6.1 [CI: 0.9; 12.6]) and functional capacity measured using the 30″ sit-to-stand test (PACS delta = 2.4 [CI: 1.2; 3.6]). The same-day hospital leave was high in the SSPP group (54.5%). Our pilot telehealth PP seems to be safe, feasible, and well accepted and may procure clinical and patient-centered gains that need to be confirmed in a larger trial.https://www.mdpi.com/1718-7729/32/1/55cancerexercisepreoperative exercisediet therapypsychosocial interventionquality of life |
| spellingShingle | Elise P. Legault Paula A. B. Ribeiro Danielle Moreau-Amaru Emmanuelle Robert Sara Forte Alain S. Comtois Vanessa Samouëlian François Tournoux The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia Current Oncology cancer exercise preoperative exercise diet therapy psychosocial intervention quality of life |
| title | The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia |
| title_full | The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia |
| title_fullStr | The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia |
| title_full_unstemmed | The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia |
| title_short | The PREPARE Study: Acceptability and Feasibility of a Telehealth Trimodal Prehabilitation Program for Women with Endometrial Neoplasia |
| title_sort | prepare study acceptability and feasibility of a telehealth trimodal prehabilitation program for women with endometrial neoplasia |
| topic | cancer exercise preoperative exercise diet therapy psychosocial intervention quality of life |
| url | https://www.mdpi.com/1718-7729/32/1/55 |
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