Super-resolution imaging informed scRNA sequencing analysis reveals the critical role of GDF15 in rejuvenating aged hematopoietic stem cells

Super-resolution imaging informed scRNA sequencing analysis reveals the critical role of GDF15 in rejuvenating aged hematopoietic stem cells

Although changes in mitochondrial morphology consistently associated with the aging of hematopoietic stem cells (HSCs), the specific molecular and cellular mechanisms involved are partially unclear. Live-cell super-resolution (SR) microscopy has been used to identify distinct HSC subsets that charac...

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Bibliographic Details
Main Authors:	Zhongyu Shi, Xuefei Zhang, Huihui Yang, Xiaolu Zheng, Mengxiao Niu, Yongjian Zhang, Pengfei Yuan, Wensheng Wei, Gang Huang, Riguo Fang, Liangyi Chen
Format:	Article
Language:	English
Published:	Wolters Kluwer Health 2025-06-01
Series:	Blood Science
Online Access:	http://journals.lww.com/10.1097/BS9.0000000000000236
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