Hsp90 inhibition decreases mitochondrial protein turnover.

<h4>Background</h4>Cells treated with hsp90 inhibitors exhibit pleiotropic changes, including an expansion of the mitochondrial compartment, accompanied by mitochondrial fragmentation and condensed mitochondrial morphology, with ultimate compromise of mitochondrial integrity and apoptosi...

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Bibliographic Details
Main Authors: Daciana H Margineantu, Christine B Emerson, Dolores Diaz, David M Hockenbery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-10-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0001066&type=printable
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