Dual-antigen fusion protein vaccination induces protective immunity against Candida albicans infection in mice

Dual-antigen fusion protein vaccination induces protective immunity against Candida albicans infection in mice

Candida albicans Is a leading cause of nosocomial bloodstream infections, particularly in immunocompromised patients. Current therapeutic strategies are insufficient, highlighting the need for effective vaccines. This study aimed to evaluate the efficacy of a dual-antigen fusion protein vaccine (AH)...

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Bibliographic Details
Main Authors: Keran Jia, Yanhao Zhang, Mengyu Jiang, Mengge Cui, Jia Wang, Jiajia Zhang, Hua Wang, Huihai Zhao, Mengyan Li, Quanming Zou, Hao Zeng
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Candida albicans vaccine
dual-antigen fusion protein (AH)
antifungal efficacy
humoral immune response
rabbit models
Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2024.2406065
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