Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis
Pleomorphic xanthoastrocytoma (PXA) is a primary central nervous system tumor characterized primarily by epileptic seizures as its clinical manifestation. Due to overlapping clinical and radiological findings with other intracranial tumors, and its rarity in clinical settings, PXA is easily misdiagn...
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Editorial Office of Computerized Tomography Theory and Application
2025-07-01
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| Series: | CT Lilun yu yingyong yanjiu |
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| Online Access: | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2024.090 |
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| author | Xiaojun SHEN Yuhua LU Zonghui LIANG |
| author_facet | Xiaojun SHEN Yuhua LU Zonghui LIANG |
| author_sort | Xiaojun SHEN |
| collection | DOAJ |
| description | Pleomorphic xanthoastrocytoma (PXA) is a primary central nervous system tumor characterized primarily by epileptic seizures as its clinical manifestation. Due to overlapping clinical and radiological findings with other intracranial tumors, and its rarity in clinical settings, PXA is easily misdiagnosed. Here, we report a case of PXA in a 16-year-old male who experienced a sudden epileptic seizure. Cranial magnetic resonance imaging (MRI) showed a cystic-solid lesion in the left temporal lobe, which was interpreted as a possible glioma. The patient underwent a gross total resection of the tumor, and the pathological examination confirmed the diagnosis of PXA (World Health Organization grade 2). After the previous treatment, the patient did not experience any epileptic seizures. During a follow-up period of approximately 1 year, a cranial MRI indicated no signs of tumor recurrence. In this report, a comprehensive literature review based on the imaging findings in this case was conducted to summarize the imaging features of PXA, aiming to enhance the clinicians’ understanding and provide guidance for accurate diagnosis. |
| format | Article |
| id | doaj-art-137db9b4b43244148c963f3a67fe917a |
| institution | OA Journals |
| issn | 1004-4140 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Editorial Office of Computerized Tomography Theory and Application |
| record_format | Article |
| series | CT Lilun yu yingyong yanjiu |
| spelling | doaj-art-137db9b4b43244148c963f3a67fe917a2025-08-20T02:36:03ZengEditorial Office of Computerized Tomography Theory and ApplicationCT Lilun yu yingyong yanjiu1004-41402025-07-0134470370610.15953/j.ctta.2024.0902024.090Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case AnalysisXiaojun SHEN0Yuhua LU1Zonghui LIANG2Department of Radiology, Jing’an District Central Hospital (Jing’an Branch of Huashan Hospital affiliated with Fudan University), Shanghai 200040, ChinaDepartment of Radiology, Jing’an District Central Hospital (Jing’an Branch of Huashan Hospital affiliated with Fudan University), Shanghai 200040, ChinaDepartment of Radiology, Jing’an District Central Hospital (Jing’an Branch of Huashan Hospital affiliated with Fudan University), Shanghai 200040, ChinaPleomorphic xanthoastrocytoma (PXA) is a primary central nervous system tumor characterized primarily by epileptic seizures as its clinical manifestation. Due to overlapping clinical and radiological findings with other intracranial tumors, and its rarity in clinical settings, PXA is easily misdiagnosed. Here, we report a case of PXA in a 16-year-old male who experienced a sudden epileptic seizure. Cranial magnetic resonance imaging (MRI) showed a cystic-solid lesion in the left temporal lobe, which was interpreted as a possible glioma. The patient underwent a gross total resection of the tumor, and the pathological examination confirmed the diagnosis of PXA (World Health Organization grade 2). After the previous treatment, the patient did not experience any epileptic seizures. During a follow-up period of approximately 1 year, a cranial MRI indicated no signs of tumor recurrence. In this report, a comprehensive literature review based on the imaging findings in this case was conducted to summarize the imaging features of PXA, aiming to enhance the clinicians’ understanding and provide guidance for accurate diagnosis.https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2024.090mripleomorphic xanthoastrocytomadiagnosis |
| spellingShingle | Xiaojun SHEN Yuhua LU Zonghui LIANG Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis CT Lilun yu yingyong yanjiu mri pleomorphic xanthoastrocytoma diagnosis |
| title | Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis |
| title_full | Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis |
| title_fullStr | Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis |
| title_full_unstemmed | Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis |
| title_short | Diagnosis of Pleomorphic Xanthoastrocytoma with Enhanced MRI Examination: A Clinical Case Analysis |
| title_sort | diagnosis of pleomorphic xanthoastrocytoma with enhanced mri examination a clinical case analysis |
| topic | mri pleomorphic xanthoastrocytoma diagnosis |
| url | https://www.cttacn.org.cn/cn/article/doi/10.15953/j.ctta.2024.090 |
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