Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art

Since the increasing update of the biomolecular scientific literature, biomarkers in stroke have reached an outstanding and remarkable revision in the very recent years. Besides the diagnostic and prognostic role of some inflammatory markers, many further molecules and biological factors have been a...

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Main Authors: Marialuisa Gandolfi, Nicola Smania, Antonio Vella, Alessandro Picelli, Salvatore Chirumbolo
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2017/1389475
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author Marialuisa Gandolfi
Nicola Smania
Antonio Vella
Alessandro Picelli
Salvatore Chirumbolo
author_facet Marialuisa Gandolfi
Nicola Smania
Antonio Vella
Alessandro Picelli
Salvatore Chirumbolo
author_sort Marialuisa Gandolfi
collection DOAJ
description Since the increasing update of the biomolecular scientific literature, biomarkers in stroke have reached an outstanding and remarkable revision in the very recent years. Besides the diagnostic and prognostic role of some inflammatory markers, many further molecules and biological factors have been added to the list, including tissue derived cytokines, growth factor-like molecules, hormones, and microRNAs. The literatures on brain derived growth factor and other neuroimmune mediators, bone-skeletal muscle biomarkers, cellular and immunity biomarkers, and the role of microRNAs in stroke recovery were reviewed. To date, biomarkers represent a possible challenge in the diagnostic and prognostic evaluation of stroke onset, pathogenesis, and recovery. Many molecules are still under investigation and may become promising and encouraging biomarkers. Experimental and clinical research should increase this list and promote new discoveries in this field, to improve stroke diagnosis and treatment.
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spelling doaj-art-1376d8c461824fc8b4df196c78c6fc552025-08-20T02:04:49ZengWileyNeural Plasticity2090-59041687-54432017-01-01201710.1155/2017/13894751389475Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the ArtMarialuisa Gandolfi0Nicola Smania1Antonio Vella2Alessandro Picelli3Salvatore Chirumbolo4Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyImmunology Unit, Azienda Ospedaliera Universitaria Integrata, Verona, ItalyDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, ItalyDepartment of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, ItalySince the increasing update of the biomolecular scientific literature, biomarkers in stroke have reached an outstanding and remarkable revision in the very recent years. Besides the diagnostic and prognostic role of some inflammatory markers, many further molecules and biological factors have been added to the list, including tissue derived cytokines, growth factor-like molecules, hormones, and microRNAs. The literatures on brain derived growth factor and other neuroimmune mediators, bone-skeletal muscle biomarkers, cellular and immunity biomarkers, and the role of microRNAs in stroke recovery were reviewed. To date, biomarkers represent a possible challenge in the diagnostic and prognostic evaluation of stroke onset, pathogenesis, and recovery. Many molecules are still under investigation and may become promising and encouraging biomarkers. Experimental and clinical research should increase this list and promote new discoveries in this field, to improve stroke diagnosis and treatment.http://dx.doi.org/10.1155/2017/1389475
spellingShingle Marialuisa Gandolfi
Nicola Smania
Antonio Vella
Alessandro Picelli
Salvatore Chirumbolo
Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art
Neural Plasticity
title Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art
title_full Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art
title_fullStr Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art
title_full_unstemmed Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art
title_short Assessed and Emerging Biomarkers in Stroke and Training-Mediated Stroke Recovery: State of the Art
title_sort assessed and emerging biomarkers in stroke and training mediated stroke recovery state of the art
url http://dx.doi.org/10.1155/2017/1389475
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