Cellulose-based suture: State of art, challenge, and future outlook

Surgical sutures as the most widely used and high-value implanted materials are of vital importance in wound closure and healing. Among them, cellulose-based sutures with multifunctionality have been developed in recent decades, and are very promising to replace the fossil-based synthetic sutures. T...

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Main Authors: Meiyan Wu, Lei Ding, Xiaoying Bai, Yuxiang Cao, Mehdi Rahmaninia, Bing Li, Bin Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-08-01
Series:Journal of Bioresources and Bioproducts
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Online Access:http://www.sciencedirect.com/science/article/pii/S2369969824000811
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author Meiyan Wu
Lei Ding
Xiaoying Bai
Yuxiang Cao
Mehdi Rahmaninia
Bing Li
Bin Li
author_facet Meiyan Wu
Lei Ding
Xiaoying Bai
Yuxiang Cao
Mehdi Rahmaninia
Bing Li
Bin Li
author_sort Meiyan Wu
collection DOAJ
description Surgical sutures as the most widely used and high-value implanted materials are of vital importance in wound closure and healing. Among them, cellulose-based sutures with multifunctionality have been developed in recent decades, and are very promising to replace the fossil-based synthetic sutures. Therefore, this paper aims at covering the history and recent advances of cellulose-based suture, mainly including the materials used (e.g., natural cellulose, nanocellulose, and regenerated cellulose), fabrication methods and mechanism of wet spinning and the recently developed interfacial polyelectrolyte complexation spinning, as well as suture application performance (such as mechanical properties, cytocompatibility, biodegradability, absorbable properties, and antibacterial properties). More importantly, it summarizes all cellulose-based sutures, and then delves deep into the challenges and future outlook. Thus, this review provides an important reference for the development of high-end cellulose-based medical sutures.
format Article
id doaj-art-136cbf496431471c84bbc9bb018bff0a
institution DOAJ
issn 2369-9698
language English
publishDate 2025-08-01
publisher KeAi Communications Co., Ltd.
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series Journal of Bioresources and Bioproducts
spelling doaj-art-136cbf496431471c84bbc9bb018bff0a2025-08-20T03:02:36ZengKeAi Communications Co., Ltd.Journal of Bioresources and Bioproducts2369-96982025-08-0110329530910.1016/j.jobab.2024.11.006Cellulose-based suture: State of art, challenge, and future outlookMeiyan Wu0Lei Ding1Xiaoying Bai2Yuxiang Cao3Mehdi Rahmaninia4Bing Li5Bin Li6CAS Key Laboratory of Biobased Materials, Qingdao New Energy Shandong Laboratory, System Integration Engineering Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, ChinaQingdao Hospital of Traditional Chinese Medicine (Municipal Hiser Hospital), Qingdao 266033, ChinaQingdao Hospital of Traditional Chinese Medicine (Municipal Hiser Hospital), Qingdao 266033, ChinaCAS Key Laboratory of Biobased Materials, Qingdao New Energy Shandong Laboratory, System Integration Engineering Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, ChinaWood and Paper Science and Technology Department, Faculty of Natural Resources, Tarbiat Modares University, Noor 46417-76489, IranQingdao Hospital of Traditional Chinese Medicine (Municipal Hiser Hospital), Qingdao 266033, China; Corresponding authors.CAS Key Laboratory of Biobased Materials, Qingdao New Energy Shandong Laboratory, System Integration Engineering Center, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China; Shandong Energy Institute, Qingdao 266101, China; Corresponding authors.Surgical sutures as the most widely used and high-value implanted materials are of vital importance in wound closure and healing. Among them, cellulose-based sutures with multifunctionality have been developed in recent decades, and are very promising to replace the fossil-based synthetic sutures. Therefore, this paper aims at covering the history and recent advances of cellulose-based suture, mainly including the materials used (e.g., natural cellulose, nanocellulose, and regenerated cellulose), fabrication methods and mechanism of wet spinning and the recently developed interfacial polyelectrolyte complexation spinning, as well as suture application performance (such as mechanical properties, cytocompatibility, biodegradability, absorbable properties, and antibacterial properties). More importantly, it summarizes all cellulose-based sutures, and then delves deep into the challenges and future outlook. Thus, this review provides an important reference for the development of high-end cellulose-based medical sutures.http://www.sciencedirect.com/science/article/pii/S2369969824000811CelluloseSurgical sutureNanocelluloseBiodegradabilityMultifunctionality
spellingShingle Meiyan Wu
Lei Ding
Xiaoying Bai
Yuxiang Cao
Mehdi Rahmaninia
Bing Li
Bin Li
Cellulose-based suture: State of art, challenge, and future outlook
Journal of Bioresources and Bioproducts
Cellulose
Surgical suture
Nanocellulose
Biodegradability
Multifunctionality
title Cellulose-based suture: State of art, challenge, and future outlook
title_full Cellulose-based suture: State of art, challenge, and future outlook
title_fullStr Cellulose-based suture: State of art, challenge, and future outlook
title_full_unstemmed Cellulose-based suture: State of art, challenge, and future outlook
title_short Cellulose-based suture: State of art, challenge, and future outlook
title_sort cellulose based suture state of art challenge and future outlook
topic Cellulose
Surgical suture
Nanocellulose
Biodegradability
Multifunctionality
url http://www.sciencedirect.com/science/article/pii/S2369969824000811
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AT xiaoyingbai cellulosebasedsuturestateofartchallengeandfutureoutlook
AT yuxiangcao cellulosebasedsuturestateofartchallengeandfutureoutlook
AT mehdirahmaninia cellulosebasedsuturestateofartchallengeandfutureoutlook
AT bingli cellulosebasedsuturestateofartchallengeandfutureoutlook
AT binli cellulosebasedsuturestateofartchallengeandfutureoutlook