Reprogramming of hsa_circ_0008719 and its target miR-3615 induced by TOB1 in exosomes of gastric cancer cells: a contribution to inhibit gastric cancer progression

Abstract Circular RNAs (circRNAs) are highly stable and abundant in tumor-derived exosomes, where they often function as microRNA (miRNA) sponges to regulate gene expression and biological processes. Previous research showed that Transducer of ERBB2.1 (TOB1) overexpression induces autophagy and supp...

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Bibliographic Details
Main Authors: Na Qian, Tongtong Huang, Lulu Zhang, Li Zhang, Lijie Zhou, Dong Wang, Xiao Liang, Songbin Fu, Yingwei Xue, Jingcui Yu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-12789-8
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