Age-Related Decline of Gastric Secretion: Facts and Controversies

Age-Related Decline of Gastric Secretion: Facts and Controversies

Aging is associated with structural and functional changes in the gastrointestinal tract; however, its impact on gastric secretion remains unclear. This scoping review examines whether gastric secretion declines with age and explores its clinical implications. Following the PRISMA guidelines, PubMed...

Full description

Saved in:

Bibliographic Details
Main Authors:	Francisco Vara-Luiz, Ivo Mendes, Carolina Palma, Paulo Mascarenhas, Gonçalo Nunes, Marta Patita, Jorge Fonseca
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Biomedicines
Subjects:	aging gastric secretion chronic atrophic gastritis <i>Helicobacter pylori</i> precision medicine
Online Access:	https://www.mdpi.com/2227-9059/13/7/1546
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Helicobacter pylori infection and serum pepsinogen concentrations in an elderly population representative of Costa Rica
by: Clas Une, et al.
Published: (2022-01-01)

Combination of artificial intelligence endoscopic diagnosis and Kimura‐Takemoto classification determined by endoscopic experts may effectively evaluate the stratification of gastric atrophy in post‐eradication status
by: Kumiko Kirita, et al.
Published: (2025-04-01)

The prevalence of atrophic gastritis of the body of stomach at Krasnoyarsk population over 45 years old
by: V. V. Tsukanov, et al.
Published: (2012-07-01)

Endoscopic diagnosis and prevalence of early gastric cancer in India: A prospective study
by: Ashutosh Mohapatra, et al.
Published: (2024-04-01)

Helicobacter pylori eradication and gastric cancer prevention in a pooled analysis of large-scale cohort studies in Japan
by: Ayami Ono, et al.
Published: (2025-07-01)

A Prospective Study on the Detection of Gastric Neoplasms Using Pepsinogen and Gastrin-17 Levels
by: Sun-Young Lee, et al.
Published: (2025-07-01)

Predictive Factors for Improvement of Atrophic Gastritis and Intestinal Metaplasia: A Long-term Prospective Clinical Study
by: Young-Jae Hwang, et al.
Published: (2018-09-01)

Association of Helicobacter pylori related chronic atrophic gastritis and gastric cancer risk: a literature review
by: Zefeng Zhang, et al.
Published: (2025-02-01)

Corrigendum: Association of Helicobacter pylori related chronic atrophic gastritis and gastric cancer risk: a literature review
by: Zefeng Zhang, et al.
Published: (2025-03-01)

Comparative characteristics of cytokine regulation in patients with gastric diseases associated with <i>Helicobacter pylori</i> infection
by: O. V. Smirnova, et al.
Published: (2023-06-01)

Association of Helicobacter pylori vacA polymorphisms with the risk of gastric precancerous lesions in a Moroccan population
by: Mohamed Reda Jouimyi, et al.
Published: (2021-08-01)

Detection Rate of Helicobacter Pylori Infection and Atrophic Gastritis Using Serological Markers “GastroPanel®” Among Employees of the National Medical Research Radiological Centre of the Ministry of Health of the Russian Federation
by: A. D. Kaprin, et al.
Published: (2024-05-01)

Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials
by: Young-Jae Hwang, et al.
Published: (2018-12-01)

Dysregulated gastric microbial communities and functional shifts in chronic atrophic versus non-atrophic gastritis: a Helicobacter pylori-Negative observational study
by: Hong Yao, et al.
Published: (2025-04-01)

Comparative genomic analysis of Helicobacter pylori isolates from gastric cancer and gastritis in China
by: Peng-fei Kong, et al.
Published: (2025-04-01)

The persistence of Epstein-Barr virus in the gastric mucosa in patients with chronic <i>Helicobacter pylori</i>-induced gastritis with gastric erosions and the effect on the course of the disease depending on the therapy
by: E. E. Dubskaya, et al.
Published: (2021-11-01)

Spectrum of Chronic Gastritis Based on Morphological Examination of Gastric Biopsies
by: А. S. Tertychnyy, et al.
Published: (2024-05-01)

Endoscopic Diagnosis of Early Gastric Cancer and High-Risk Gastritis
by: Hidekazu Suzuki, et al.
Published: (2024-12-01)

Evaluation of upper endoscopic findings in patients with restless legs syndrome and gastric complaints
by: Mustafa ÇAM, et al.

IL-17 signaling protects against Helicobacter pylori-induced gastric cancer
by: Lee C. Brackman, et al.
Published: (2024-12-01)

Rebamipide during chronic gastritis: <i>H. pylori</i> eradication therapy and restoration of gastric mucosa barrier function
by: Т. L. Lapina, et al.
Published: (2024-01-01)

Gastric Polyps and Atrophic Gastritis
by: I. Yu. Kolesnikova, et al.
Published: (2021-06-01)

Characteristics of gastric and duodenal mucosa in patients with primary biliary cholangitis
by: Popović Dragan, et al.
Published: (2019-01-01)

Functional Dyspepsia with Helicobacter pylori Infection
by: Rabbinu Rangga Pribadi, et al.
Published: (2017-08-01)

Functional Dyspepsia with Helicobacter pylori Infection
by: Rabbinu Rangga Pribadi, et al.
Published: (2017-08-01)

Clinical and Morphological Manifestations of Gastritis and Serum Cytokine Levels in Schoolchildren with Familial History of Gastric Cancer
by: T. V. Polivanova, et al.
Published: (2021-10-01)

The results of the effectiveness of pharmaceutical treatment of chronic gastritis with erosions associated with <i>Helicobacter pylori</i>with azithromycin and amoxicillin in the elderly
by: T. E. Afanasenkova, et al.
Published: (2024-04-01)

Delayed Diagnosis and Evolving Trends in Gastric Cancer During and After COVID-19: A Comparative Study of Staging, <i>Helicobacter pylori</i> Infection and Bleeding Risk in Western Romania
by: Patricia Serena, et al.
Published: (2025-04-01)

Multiple gastric tumors in patients with combined autoimmune and helicobacter pylori-associated gastritis: a case report and literature review
by: Wulian Lin, et al.
Published: (2025-05-01)

Disruption of the biorhythm in gastric epithelial cell triggers inflammation in Helicobacter pylori-associated gastritis by aberrantly regulating NFIL3 via CagA activated ERK-SP1 pathway
by: Yongsheng Teng, et al.
Published: (2025-06-01)

Validation of a Novel Endoscopic Feature that Predicts Helicobacter pylori-negative Status: Does the Scratch Sign Reflect H. pylori Non-infection?
by: Jun-young Seo, et al.
Published: (2023-09-01)

Dysplasia of stomach epithelium at chronic <i>H. pylori</i>-associated gastritis: is everything quite so simple?
by: T. L. Lapina, et al.
Published: (2015-07-01)

Efficacy analysis of folic acid in chronic atrophic gastritis with Helicobacter pylori infection: a systematic review and meta-analysis
by: Hui Li, et al.
Published: (2025-02-01)

Pathogenicity and virulence of Helicobacter pylori: A paradigm of chronic infection
by: Marguerite Clyne, et al.
Published: (2025-12-01)

Detection of autoantibodies against carbonic anhydrase I and II in the plasma of patients with gastric cancer
by: Ahmet Mentese, et al.
Published: (2017-05-01)

<i>Helicobacter pylori</i> Vaccine: Mechanism of Pathogenesis, Immune Evasion and Analysis of Vaccine Types
by: Jingwen Gong, et al.
Published: (2025-05-01)

Medical budgeting at treatment sick Helicobacter-associations the chronic gastritis at stationary and out-patient-polyclinic stages
by: Ye. V. Sosnovskaya, et al.
Published: (2010-06-01)

IMPACT OF CLINICAL AND IMMUNOLOGICAL PARAMETERS ON THE FREQUENCY AND PREVALENCE OF HELICOBACTER PYLORI IN PATIENTS WITH RHEUMATOID ARTHRITIS
by: Sh. F. Gadieva, et al.
Published: (2018-01-01)

Does bile reflux reduce Helicobacter pylori gastritis?
by: Ezgi Kıran Taşcı, et al.
Published: (2022-02-01)

Chronic gastritis: from histological protocol to substantiation of etiopathogenetic therapy
by: I. V. Dolgalev, et al.
Published: (2021-06-01)