Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization

Conclusion: The present study explored a promising mechanism of the periodontal regeneration function of PRF, by inducing macrophage polarization, thereby enhancing osteoblast recruitment, with horizontal centrifugation significantly improving these findings.

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Main Authors: Hudi Xu, Huan Jing, Richard J. Miron, Yulan Wang, Dagang Xu, Xiaoxin Zhang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/sci/9912405
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author Hudi Xu
Huan Jing
Richard J. Miron
Yulan Wang
Dagang Xu
Xiaoxin Zhang
author_facet Hudi Xu
Huan Jing
Richard J. Miron
Yulan Wang
Dagang Xu
Xiaoxin Zhang
author_sort Hudi Xu
collection DOAJ
description Conclusion: The present study explored a promising mechanism of the periodontal regeneration function of PRF, by inducing macrophage polarization, thereby enhancing osteoblast recruitment, with horizontal centrifugation significantly improving these findings.
format Article
id doaj-art-1359bc42a0be4a229a59cf58c28af9f2
institution Kabale University
issn 1687-9678
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Stem Cells International
spelling doaj-art-1359bc42a0be4a229a59cf58c28af9f22025-08-23T00:00:04ZengWileyStem Cells International1687-96782025-01-01202510.1155/sci/9912405Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage PolarizationHudi Xu0Huan Jing1Richard J. Miron2Yulan Wang3Dagang Xu4Xiaoxin Zhang5Department of Oral ImplantologyDepartment of EndodonticsDepartment of PeriodontologyThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of EducationSchool of StomatologyThe State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) and Key Laboratory of Oral Biomedicine Ministry of EducationConclusion: The present study explored a promising mechanism of the periodontal regeneration function of PRF, by inducing macrophage polarization, thereby enhancing osteoblast recruitment, with horizontal centrifugation significantly improving these findings.http://dx.doi.org/10.1155/sci/9912405
spellingShingle Hudi Xu
Huan Jing
Richard J. Miron
Yulan Wang
Dagang Xu
Xiaoxin Zhang
Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization
Stem Cells International
title Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization
title_full Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization
title_fullStr Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization
title_full_unstemmed Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization
title_short Platelet-Rich Fibrin Promotes Osteoblast Recruitment-Associated Periodontal Regeneration via Macrophage Polarization
title_sort platelet rich fibrin promotes osteoblast recruitment associated periodontal regeneration via macrophage polarization
url http://dx.doi.org/10.1155/sci/9912405
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AT huanjing plateletrichfibrinpromotesosteoblastrecruitmentassociatedperiodontalregenerationviamacrophagepolarization
AT richardjmiron plateletrichfibrinpromotesosteoblastrecruitmentassociatedperiodontalregenerationviamacrophagepolarization
AT yulanwang plateletrichfibrinpromotesosteoblastrecruitmentassociatedperiodontalregenerationviamacrophagepolarization
AT dagangxu plateletrichfibrinpromotesosteoblastrecruitmentassociatedperiodontalregenerationviamacrophagepolarization
AT xiaoxinzhang plateletrichfibrinpromotesosteoblastrecruitmentassociatedperiodontalregenerationviamacrophagepolarization